Also known as: MHC I, H2Kb, H2-Kb, H2K-b, MHCI Clone: AF6-88.5.5.3 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 46-5958 Cat. No. Size 46-5958-80 25 ug 46-5958-82 100 ug Description: This AF6-88.5.5.3 monoclonal antibody reacts with the ...
“经典” mhci类分子是由H-2基因复合物编码的组织相容性抗原,由与不变的 β2-微球蛋白非共价结合的高度多态性 α 链异二聚体组成。这些抗原在大多数有核细胞上表达,但在不同细胞类型上表达不同。Mhci类分子将内源合成的肽呈递给通常为细胞毒性T细胞的CD8 + T淋巴细胞。在胸腺上皮细胞上表达的MHC I类抗原...
“经典” mhci类分子是由H-2基因复合物编码的组织相容性抗原,由与不变的 β2-微球蛋白非共价结合的高度多态性 α 链异二聚体组成。这些抗原在大多数有核细胞上表达,但在不同细胞类型上表达不同。Mhci类分子将内源合成的肽呈递给CD8 + T淋巴细胞,其通常是细胞毒性T细胞。在胸腺上皮细胞上表达的MHC I类抗原...
Here we explored implications of MHCI and MHCII expression in both the primary and long-term memory anti-tumor responses generated with ISV.Methods: CD4+ or CD8+ T cells were depleted in mice during the primary anti-tumor response (i.e. B78 tumor bearing mice receiving the ISV regimen) ...
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Muscle sections of 9-month-oldNebY2303H,Y935Xand age matched wild-type littermates were labelled as described previously [54]. Briefly, after blocking, mouse IgG1antibodies against myosin heavy chain MHCI (slow myosin I; diluted 1:20, NCL-MHCs, Leica Biosystems) or MHCIIA (fast myosin ...
et al. Classical MHCI molecules regulate retinogeniculate refinement and limit ocular dominance plasticity. Neuron 64, 463–470 (2009). Article CAS PubMed PubMed Central Google Scholar Shi, Q. et al. Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice. ...
4360 (Human); 17533 (Mouse); 291327 (Rat) Alternate Names CD206; CLEC13D; CLEC13Dmacrophage mannose receptor 1; C-type lectin domain family 13 member D; mannose receptor, C type 1; MMR; MMRCD206 antigen; MRC1 Product Datasheets ...
Expression of MHCI is elevated in KRIMS-2 tumors, which also have the highest percentage of Tregs and CD8 + T cells among all models (Fig. 7A,B). We hypothesized that MHCI mRNA correlates with T infiltration across all UPS tumors. Indeed, there is a positive correlation between MHCI ...