new, spontaneous mouse lymphoma cell line displaying CD19, B220, MHC II, surface IgG2a/kappa chain and MAC-1, which is negative for CD5, animal models of B-cell lymphoma based on said cell line and methods for assessing lymphoma propagation and lymphoma expansion based on said cell line.BA...
The p53 tumor suppressor protein plays an important role in regulating the cellular response to DNA damage, including cell cycle arrest and apoptosis induction. Normal p53 function is critical for the maintenance of genomic stability. The mouse lymphoma L5178Y/TK+/−-3.7.2C cell line is widely...
The method is mutagenicity assay on mouse lymphoma cell line (L5178Y tk+/- 3.7.2C), heterozygous at the thymidine kinase locus (Tk1) on chromosome 11. Mutation on this part of the chromosome and inactivation of the tk+ allele induces trifluorothymidine (TFT) resistance, and tk -/- ...
Next, ImmuCC was used to deconvolve the immune compositions for three mouse tumor tissues obtained from subcutaneously implanted histologically distinct mouse cell lines, including Lewis lung cancer cell line (LLC), murine colon carcinoma cell line (MC38), and the T cell lymphoma cell line (EL4)...
We focused on occupancy by 32 TFs in cell line models for erythroid progenitors (mouse erythroleukaemia MEL and human leukaemia K562 cells) and lymphoblasts (mouse lymphoma CH12 and human B lymphoblastoid GM12878 cells) in mouse and human, and we also showed that the results are similar to ...
Wu, HK, Hirai, H, Inamori, K, Kitamura, K, Takaku, F (1992) Anti-tumor effects of interleukin-4, and interleukin-5 against mouse B cell lymphoma and possible mechanisms of their action. Jpn J Cancer Res 83: pp. 200Wu HK,Hirai H,Inamori K,et al.Anti-tumor effects of interleukin-...
The YAC-1 T lymphoma cell line was sensitive to dopamine with a higher magnitude than normal lymphoid cells. Dopamine was less potent than isoproterenol in all cells, and whereas dopamine-sensitive and isoproterenol-sensitive cells, or dopamine-insensitive and isoproterenol-insensitive cells were found...
MutationAdenosine deaminase-deficient mutants of a mouse lymphoma cell line S49 have been isolated by a two-step selection process. In the first step, we... TS Chan,C Huang,T Sato - 《Somatic Cell & Molecular Genetics》 被引量: 5发表: 1989年 加载更多来源...
After induction of IgH loss in the JEKO-1 cell line by transduction with either Sμ 5′/Sγ3 3′ or Sμ 3′/Sγ3 3′ gRNAs, we subsequently transduced the lymphoma cells with lentivirus expressing GFP as reporter (control vector) or GFP and PI3KδE1021K. IgH-negative lymphoma ...
In order to probe applicability of autoCSC, we prepared a dilution series from 30 to 0.1 × 106 cells of a B lymphoma cell line and quantified N-glycoproteins. Compared to the number of surface proteins identified from a sample of 30 × 106 cells, we recovered a median of 62...