(aa) core FGF domain that exhibits a beta -trefoil structure (1, 2). Unlike other FGF subfamilies, FGF-19 subfamily members exist as highly diffusible molecules that is attributed to poor ECM/heparin sulfate binding (3-6). The cDNA for mouse FGF-23 predicts a 251 aa polypeptide that ...
Upregulated by IL-2, FGF-basic, EGF; downregulated by 1-α-25-Dihydroxy vitamin D3, dexamethasone Gene ID 15978 View all products for this Gene ID UniProt View information about IFN-gamma on UniProt.org Documentation Technical Data Sheet (pdf) Certificate of Analysis Safety Data ...
Forty-eight cytokines including FGF basic, Eotaxin (also known as CCL11), G-CSF (CSF3), GMCSF (CSF2), IFN-γ, IL-1β, IL-1RA, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8 (also known as CXCL8), IL-9, IL-10, IL-12 (p70), IL-13, IL-15, IL-17α, IP10 (CXCL10), ...
(Sigma), 10 mM nicotinamide (Sigma), 1% insulin-transferrin-selenium (ITS) premix (Gibco), 5 ml of PSG, 10 ng/ml fibroblast growth factor 4 (FGF4) (Peprotech), 10 ng/ml hepatocyte growth factor (HGF) (Peprotech), and 10 ng/ml epidermal growth factor (EGF) (Pepro...
C1q R1/CD93FGF-21Lipocalin-2/NGAL, CCL2/JE/MCP-1Flt-3 LigandLIX CCL3/CCL4 MIP-1 alpha/betaGas6M-CSF CCL5/RANTESG-CSFMMP-2 CCL6/C10GDF-15MMP-3 CCL11/EotaxinGM-CSFMMP-9 CCL12/MCP-5HGFMyeloperoxidase CCL17/TARCICAM-1/CD54Osteopontin (OPN) ...
FGF2 | FIGF | FLT1 | FLT3LG | FLT4 | FRZB | GAS1 | GAS6 | GPNMB | GREM1 | GRN | GZMB | H60A | HAVCR1 | HGF | ICAM1 | IFNA11 | IFNG | IFNGR1 | IFNL2 | IGDCC4 | IGF1 | IGFBP2 | IGFBP3 | IGFBP5 | IGFBP6 | IL10 | IL12A | IL12B | IL13 | IL15 | IL17A ...
Treatment with rhFGF21, by inhibiting NF-κB, helps alleviate neuroinflammation mediated by microglia/macrophages and reduces immune cell infiltration following brain I/R. In this study, the role of RPS27A in brain I/R injury is mediated through the regulation of the PSMD12/NF-κB pathway. ...
Fibroblast growth factor 16 (FGF-16) belongs to the large FGF family which has at least 23 members (1). All FGF family members are heparin-binding growth factors with a core 120 amino acid (aa) FGF domain that allows for a common tertiary structure. FGFs are expressed during embryonic dev...
The cytokines/chemokines measured were the following: FGFb, GM-CSF, IFNγ, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12, IL-13, IL-17, IP-10, KC, MCP-1, MIG, MIP-1α, TNFα, and VEGF. Splenocyte cellular composition and intracellular cytokine analysis ...
During the time these mouse KOs were being characterized two inde- pendent groups demonstrated that FAM20C is a Golgi kinase that phosphorylates proteins undergoing secre- tion.60–61 FAM20C has recently been shown to phosphory- late FGF23 at serine 180, inhibiting O-glycosylation of Table 1....