CD8a 53-6.7 Rat IgG2ak Cytotoxic T cell marker CoraLite Plus 488 (493 nm/522 nm) CL488-65105 CD69 H1.2F3 Armenian Hamster IgG Marker of activation CoraLite Plus 750 (755 nm/780 nm) CL750-65137 CD25 PC61.5 Rat IgG1λ Marker of activation Storage Storage Buffer: PBS with 0.09% so...
CD8a 53-6.7 Rat IgG2ak Cytotoxic T cell marker CoraLite Plus 488 (493 nm/522 nm) CL488-65105 CD69 H1.2F3 Armenian Hamster IgG Marker of activation CoraLite Plus 750 (755 nm/780 nm) CL750-65137 CD25 PC61.5 Rat IgG1λ Marker of activation 保存条件 保存缓冲液:含有0.09% NaN3的PBS。
CD8A (Cytotoxic- & Suppressor T-Cell Marker) Mouse Monoclonal Antibody 供应商 MyBioSource 产品货号 MBS438091 产品报价 ¥询价/0.02mg(WithBSA&Azideat0.2mg/mL) ¥询价/0.1mg(WithBSA&Azideat0.2mg/mL) ¥询价/其它规格 产品说明书 点击查看
Treatment of 6-month-old mice with anti-programmed cell death protein (PD-1) and anti-cytotoxic T lymphocyte-associated protein 4 (CTLA-4) antibodies for 6 weeks resulted in an increase in the number of CD8+ T cells (Extended Data Fig. 4a). The treatment did not lead to significant ...
Using this format, we generated a bispecific antibody, REGN1979, targeting the B cell marker, CD20 and the CD3 component of the T cell receptor, which triggers redirected killing of B cells. In mice, this antibody prevented growth of B cell tumors and also caused regression of large ...
Thy-1 (CD90) is a 25-37 kDa glycosylphosphatidylinositol (GPI) -anchored glycoprotein expressed on many cell types, including T cells, thymocytes, neurons, endothelial cells, and fibroblasts. Activation of Thy-1 can promote T cell activation, and this role of Thy-1 is reviewed elsewhere. Thy...
Parvoviruses Minute virus of mice (MVM)Mouse parvovirus (MPV) Self-limitingAsymptomatic Can distort biological responses that depend on cell proliferation, primarily on immune cells such as cytotoxic T cells. Lymphocytic Choriomeningitis virus (LCMV) IC—self-limiting and asymptomaticIn others it can ...
cell-to-cell contact mechanisms that may involve the release of cytotoxic molecules including perforin and granzymes A and B.28In particular, gene expression arrays showed that granzyme B was upregulated in mouse Tregs.29Also, human Tregs that expressed granzyme A were cytotoxic to CD4+and CD8+...
Roseburia spp: a marker of health? Future Microbiol. 2017;12:157–70. Article CAS PubMed Google Scholar Kang X, et al. Roseburia intestinalis generated butyrate boosts anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8(+) T cells. Gut. 2023;72(11):2112–22. Article CAS...
NK1.1+CD8 T cells from OT-I mice performed rapid and vigorous killing of tumor cells, while the NK1.1− cytotoxic T lymphocyte (CTL) population failed to exhibit potent antitumor effects, indicative of the more efficient tumoricidal effects of CD8+NKT-like cells [17]. Although the ...