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Then isoflurane was discontinued to allow mice to wake up and return to the home cage. Carprofen (5 mg/kg) and enrofloxacin (5 mg/kg) were subcutaneously given before surgery and 3 days after surgery. The liver region of the mice was imaged by the dual-modality PA and ultrasound ...
2. This cell population exerts crucial functions for the maintenance of brain tissue homeostasis during development as well as in adulthood, both in physiological and pathological conditions3. In fact, microglia cells actively
The ‘experimental cage’ was a standard small rodent cage with standard bedding but without access to food or water. Next, the mice were habituated to the RAM where they were allowed to freely explore for 30 min (all arms open). While in the maze, animals were also exposed to strawberry...
Upon completion of imaging, the animal was allowed to fully recover from anesthesia before being returned to its home cage. Using the spatiotemporal multiplexing, a structural volumetric stack was simultaneously acquired with the TeFo and the DL 2p path. Small capillaries (∼3μm diameter) at ...
At the end of the training trial, the mice were removed from the apparatus and kept in an individual cage during the inter-trial intervals. Mice were first tested in the object displacement test and then tested 12 h later in the modified Y-maze test, based on our previous validation that...
The ani- mals were kept in groups of one to five mice per cage in a room with a 12-h light cycle (lights on at 6:00 AM and off at 6:00 PM) at 23 °C with food and water available ad libitum. Male and female mice were randomized across the groups, with each group having ...
The CP-Tg, containing a hybrid enzyme of COX-1 linked to PGIS (COX-1-10aa-PGIS), and WT mice used in the experiments were maintained in the Animal Care Facility at the University of Houston. The animals were kept in groups of one to five mice per cage in a room with a 12-h lig...
BxD2/TyJ and Cast/EiJ strains at equal strain and sex distribution. Mice were intercrossed for 20 generations with at least 50 breeding pairs per generation. Offspring mice used in this study were transferred into separate cages after weaning at 3–4 weeks. Each cage contained mice of either...