ResultsSnord116del mice born and maintained at TN exhibited lower body weight curves, lower percentage fat mass, and lower food intake than WT mice at RT. In 4- to 6-month-old high-fat diet-fed female mice, TN raised the Snord116del body weight curve closer to that of RT-housed WT...
We then extracted anterior–posterior cell rankings by taking the rank of the fitted arc length from the beginning of the curve, ensuring that the curve always began at the anterior-most position. Joint analysis with Nowotschin et al. and Han et al. datasets To further understand the ...
Concentration values (pg ml−1) were calculated against a standard curve using provided calibrators and imported to R v4.0.1. For each analyte, missing values were replaced with either the minimum (if below-fit curve range) or maximum (if above-fit curve range) calculated concentration and...
the IIJ mice tested negative for allHelicobacterspp. (data not shown). While IIJ mice with active diarrhea had an elevated colon:body weight ratio, indicating inflammation, antibiotic treatment caused the ratio to normalize and become similar to the ratios of IIJ mice that had never had diarrhea...
The quantification of HBV DNA was performed by using a routine real time PCR procedure, described previously [34,60–64]. The HBV copy numbers were determined by SYBR Green Real time PCR Master Mix (commercially available assay kit, TOYOBO, Osaka, Japan). Melt curve analysis and agarose gel...
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Values under the fit curve range and detection range were excluded. 2.21. Colonic mucus layer staining Colonic samples were embedded in paraffin with a histokinette (Leica TP1020 Tissue Processor) using the following program: 100% ethanol – 90 min; 50% ethanol/50% histoclear – 60 min; 2 ...
Thus, the growth control pathway in which the components of the GH/IGF1 signaling systems participate constitutes the major determinant of body size. To complement this conclusion mainly based on extensive growth curve analyses, we also present details concerning the involvement of the GH/IGF1 axis...
b Body weight curves of control, heterozygous, and the homozygous mice from postnatal day 11 to 33. Two-way ANOVA, Bonferroni post hoc test; n = 4, 6, 6, 6 mice. c Kaplan–Meier survival curve of the control and homozygous mice. Gehan–Breslow–Wilcoxon test, n = 12, 11 ...
the activity recovery curve in Fig.3b (HG) and c (AG) might reflect to a recovery of the vestibular function. The activity ratio in MG reached about 35% from day 3 (as of the third day, mice stayed in microgravity for 6.5 days) to day 25 after relocation to the HCU cage and reach...