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STN neurons also express the Pitx2 gene encoding a transcription factor which is crucial for their normal development23,24. Pitx2/Vglut2 overlap is complete and covers the extent of the STN22. Both Vglut2 and Pitx2 promoters have been implemented recently in optogenetics and conditional ...
nutrients Article Efficacy of a Fatty Acids Dietary Supplement in a Polyethylene Glycol-Induced Mouse Model of Retinal Degeneration Maurizio Cammalleri 1,2,† ID , Massimo Dal Monte 1,2,*,† ID , Filippo Locri 1,3, Emma Lardner 3, Anders Kvanta 3, Dario Rusciano 4, Helder André 3,...
This strategy allowed the subsequent direct substitution of this region for the equivalent sequence block within the infectious clone of MVMp, using a SacI site engineered at the C-terminus of the VP1SR, just upstream of the VP2 start site in the MVMp infectious clone. Creation of a set ...
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While exposure to most HZE particles decreases neurogenesis in the hippocampus—a brain structure important in memory—prior work suggests that 12C does not. However, much about 12C's influence on neurogenesis remains unknown, including the time course of its impact on neurogenesis. To address this...
Moreover, double immunopositive (BrdU+/DCX+) cells showed a difference between two groups (Control vs. ASI, respectively, n = 4 per group, p < 0.05) (Figure 1C,F,I,L). Moreover, the total amount of DCX protein was elevated in the hippocampus of ASI group mice (n = 8 per group...
2.4. Antibodies Commercially available antibodies and dilutions used in Western blots include: SMAR- CAD1 (A302-593A, Bethyl, Biomol, Hamburg, Germany) 1:1000 and (HPA016737, Sigma- Alderich, St. Louis, MO, USA) 1:5000; TFIIIC90 (PA5-31288, ThermoFisher Scientific, TFS, Waltham, MA,...