PD progression may be determined by differential cellular susceptibility, related to mitochondrial function or proteostasis, differential cell-to-cell spread of pathology, or novel pathways and mechanisms. Risk factors determined from case-control studies indicate aetiological pathways and guide future prevent...
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Therefore, we independently manipulated both factors, allowing us to examine their causal effects on the neural correlates of action perception within the same participants. In three training sessions, participants gained motoric experience with a motorically unfamiliar action (e.g., handling chopsticks...
This resulted in a total of 10,041 gene sets for analysis. Statistics and software TOPMed genotype imputation was based on the TOPMed Imputation Server. Mixed effects model GWAS was performed with the gemma program version 0.94 beta.31 Genomic inflation factors were calculated with the R package ...
[3] and may result from a combination of motor and non-motor factors [4]. PD is one of the most common neurodegenerative conditions with 6.1 million people worldwide estimated to have PD in 2016 [5] with the prevalence expected to rise with the global ageing population [6]. The precise...
Most importantly, when these factors were controlled for, the (partial) correlation (Rp) between the NCE and GABA in the SMA region remained. When controlling for the amount of gray matter (GM), R1p = 0.8 (p < 0.003) and R2p = 0.53 (p < 0.04) (one-tailed). Similarly, when ...
Combined action observation and motor imagery (AOMI) training improves motor skill performance, but limited research has investigated possible moderating factors for this intervention. This study examined the influence of action observation (AO) perspective on the effectiveness of AOMI training for novices...
aonce conscientiousness had been partialled out of the correlations between procrastination and the other four trait factors, virtually none of them reached either practical or statistical significance (J. L. Johnson & Bloom, 1995; Schouwenburg & Lay,1995). Also, Schouwenburg (1995a) factor anal...
When studied in isolation, the impact of specific monogenic genetic risk factors for ASD is limited by the frequency of the mutations in the human population, which is, in general, very low36. Our results demonstrate that some of these risk factors are in fact directly connected, such that ...
respectively, than high strength boys. This finding highlights the relationship between strength and movement competency and therefore the need for resistance training in adolescence. Nonetheless, motor skill performance is primarily influenced by factors other than movement competency, such as strength and...