Myeloma is the most common primary bone malignancy and one of the most common hematologic malignancies. Research on myeloma constantly produces new information on genetic factors, imaging techniques, and treatment complications among others that is of use to patients, referring physicians, and ...
Our results provide further evidence that LOF variants in NFKB1 are the most common monogenic cause of disease to date, even in seemingly sporadic cases. In these patients there is a clear association with complications, such as malignancy, autoimmunity, and severe nonimmune liver disease; this ...
and the activa- tion of oncogenes play important roles in the carcinogenesis of a variety of solid tumors in humans (Nakamura 1993; Nakamura 1996), while chromosomal rearrangements that produce chimeric oncogenes are occasionally associated with hematologic malignancy and some sarcomas (Rabbits 1994)....
Hematologic disorders are com- plicated and deserve a separate study; electrocution was ad- dressed before [26]. We also excluded radium users, even if they had also applied X-rays, because their time characteris- tics were different and because the penetrating gamma rays and particle emissions...
Despite the quick resolution of significant coagulation disturbances, severe hemorrhage was the most frequent cause (70%) of early death, with most of the fatal bleeding events located in the CNS [175]. Differentiation syndrome (retinoic-acid-like syndrome) is relatively common (reported in 7–35...
MalignancyThe hematologic system is frequently involved in sarcoidosis. Lymphopenia is the most common hematologic manifestation noted, although anemia and thrombocytopenia also occur. The etiology of these common manifestations can be direct granulomatous infiltration of bone marrow, lymph nodes, or spleen ...
High frequency of infection with tuberculosis as the most common cause of bone marrow necrosis: a study from tertiary care centre in northern India and their clinico-pathologic analysisBone marrow necrosisTuberculosisHematologic malignanciesBone marrow necrosis (BMN) is seen in various malignant and non...