The adjusted 30-day mortality rate after TAVR fell from 10.48% (95% CI 7.97–11.65%) in 2007 to 2.27% (95% CI 1.14–4.49%) in 2016, corresponding to a relative decrease of 78% over 10 years. The adjusted mortality rate within 1 year after TAVR was 30.24% (95% CI 24.53–36.65%)...
47.1 ± 22.1 mmHg; p < 0.001) prior TAVR and smaller effective orifice area after TAVR compared to LVmrEF and LVpEF patients (1.74 ± 0.47 cm2 vs. 1.77 ± 0.44 cm2 vs. 1.81 ± 0.46 cm2; p < 0.010). However, despite a higher rate of trans-apical...
Exposures Steady state (1 month) change in kidney function after TAVR. Significant improvement or deterioration in renal function was defined as a greater than or equal to 10% change in estimated glomerular filtration rate (eGFR). Main Outcomes and Measures Overall mortality at 2-year follow-up....
Direct oral anticoagulants or vitamin K antagonists after TAVR: A systematic review and meta-analysis 3.4 Cardiovascular mortality Cardiovascular mortality (Fig. S2-A) was similar between DOACs and VKA (RR 1.03; 95% CI: 0.81–1.30; p-value 0.84; I2 = 0%). Results were confirmed in RCTs ...
4,7,24,25 To our knowledge, the present study has, for the first time, demonstrated the association of prescription of a RAS inhibitor at hospital discharge with lower mortality after TAVR and also has demonstrated an association with a lower rate of heart failure readmission. Several potential...
4,35 Still, pre-existing intrinsic patient factors (ie, severe renal, pulmonary, or cardiac dysfunction) has been suggested as independent predictors of mortality >3 years after TAVR rather than procedure related factors during the TAVR hospitalization.37 In addition to COPD, chronic renal disease ...
[27] observed that patients with PAD had a two-fold higher rate of major vascular complications after TAVR compared to patients without PAD. Because most peri-procedural vascular injuries lead to bleeding, it can be assumed that these events are more pronounced in patients with AF than in ...
TAVR+PCI was associated with higher in-hospital mortality (OR 1.66; 95% CI 1.21 - 2.27; p=0.002; Fig. 1). However, there was no difference in acute kidney injury (OR 0.59; 95% CI 0.26 - 1.32; p=0.20; Fig. 2A). Furthermore, TAVR+PCI seemed to lower the rate of major bleeding...
In this new era with expanded treatment options, patients with severe symptomatic AS who remain untreated after referral for TAVR experience a mortality rate of 39% at 1 year. The presence of advanced heart failure, renal dysfunction, low albumin, and/or left ventricular dysfunction identifies ...
The overall long-term survival rate after TAVR was 73.5% (95% confidence interval (CI): 69.8%-77.1%). Additionally, MACE occurred in 21% of patients throughout the follow-up period. The cumulative incidence of MACE at one year, three years,...