Monro-Kellie hypothesis [mun-ro´ kel´e] an explanation of the maintenance of intracranial pressure: The skull is viewed as a closed container housing brain tissue, blood, and cerebrospinal fluid; a change in any of these three components will affect the other two. If the volume added to...
Related to Monro-Kellie hypothesis:intracranial pressure a prediction derived from theoretical analysis that is couched in a form precise enough to be subjected to testing against empirical data. In economics, hypotheses are generated by a process of logical deduction from sets of initial assumptions ...
This hypothesis has substantial theoretical implications in increased intracranial pressure and in decreased CSF volume. Many of the MRI abnormalities seen in intracranial hypotension or CSF volume depletion can be explained by the Monro–Kellie hypothesis. These abnormalities include meningeal enhancement, ...
Many of the MRI abnormalities seen in intracranial hypotension or CSF volume depletion can be explained by the Monro-Kellie hypothesis. These abnormalities include meningeal enhancement, subdural fluid collections, engorgement of cerebral venous sinuses, prominence of the spinal epidural venous plexus, and...