Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases. Biomarkers Res 2014;2:1.Yang J, Zhang L, Yu C, Yang XF, Wang H. Monocyte and macrophage dif- ferentiation: circulation inflammatory monocyte as biomarker for inflam- matory diseases. ...
(angiogenesis/arteriogenesis), but also in any type oftissue damage, including host–pathogen interaction, cancer,atherosclerosis,cardiac diseasesand auto-immune diseases.Monocyteshave been recognized as cells with great plasticity, which may differentiate into DCs,macrophage subsets, and proangiogenic cells...
As CSF1R is normally reduced when monocytes differentiate into macrophages, this observation points towards a potential defect in monocyte maturation in the patient. Next, we investigated the consequences of decreased QKI expression on monocyte to macrophage differentiation. For this, we obtained freshly...
Yingqiu Li Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China Monocyte/macrophage differentiation represents a major branch of hematopoiesis and is a central event in the immune respons...
Monocytes and macrophages play an indispensable role in maintaining intestinal homeostasis and modulating mucosal immune responses in inflammatory bowel disease (IBD). Although numerous studies have described macrophage properties in IBD, the underlying
1c, e). This suggests that the largest barrier to producing an AAM may be the differentiation of a monocyte to a macrophage, rather than the polarization. While macrophages can be highly plastic in terms of phenotype there is little evidence that they dedifferentiate back into monocytes [9]....
Ly6C- MCs are recruited to tissue and differentiate into M2Mϕ, which secrete anti-inflammatory cytokine and contribute to tissue repair. TC, T cell; MC, monocyte; M ϕ, macrophage; EC, endothelial cells; DC, dendritic cell; inf., inflammatory; α-inf. Anti-inflammatory; TCR, T cell ...
Human peripheral blood mononuclear cells (PBMC) upon transendothelial migration interact with subendothelial matrix components and differentiate into macrophages. In order to study whether the shape of the cells as dictated by the extracellular matrix can influence monocyte–macrophage (mo–mφ) differentia...
Chrobok NL, Sestito C, Wilhelmus MM, et al.Is monocyte- and macrophage-derived tissue transglutaminase involved in inflammatory processes-[J] Amino Acids, 2017, 49(3): 441-452.Chrobok, N.L.; Sestito, C.; Wilhelmus, M.M.; Drukarch, B.; van Dam, A.M. Is monocyte- and macrophage-...
…wandering amoeboid cells, and the monocyte, a precursor of the macrophage, is found in the blood. The smaller phagocytes are chiefly neutrophils that are carried along by the circulating blood until they reach an area of infected tissue, where they pass through the blood vessel wall and lodg...