eicosanoids inflammation X-ray crystallography The cysteinyl leukotrienes (CysLTs), leukotriene (LT)C4, LTD4, and LTE4, are biologically active lipids involved in both acute and chronic inflammatory responses that have been shown to contribute to inflammatory bowel disease and asthma (1, 2). CysLT...
in late 20191. The virus belongs to the subgenus Sarbecovirus of the genus Betacoronavirus within the subfamily Orthocoronavirinae2. Two other zoonotic coronaviruses emerged in the last 20 years and cause severe acute respiratory
In addition to neutralization activity, Fc effector functions have also been shown to play an important functional role in protection against SARS-CoV-2 in vivo22,23,24,25. Therefore, we investigated the ability of the NTD and RBD mAbs, all expressed as IgG1, to promote Fc effector functions...