Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes ′...
蛋白别名: MADS box transcription enhancer factor 2, polypeptide C; Myocyte enhancer factor 2C; Myocyte-specific enhancer factor 2C 基因别名: 5430401D19Rik; 9930028G15Rik; AV011172; C5DELq14.3; DEL5q14.3; Mef2; MEF2C UniProt ID: (Human) Q06413, (Mouse) Q8CFN5 Entrez Gene ID: (...
蛋白别名: MADS box transcription enhancer factor 2, polypeptide C; Myocyte enhancer factor 2C; Myocyte-specific enhancer factor 2C 基因别名: C5DELq14.3; DEL5q14.3; MEF2C UniProt ID: (Human) Q06413 Entrez Gene ID: (Human) 4208 功能 RNA polymerase II regulatory region sequence-specific...
MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined...
This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein wit...
蛋白别名: DKFZp779K1053; HD7; HD9; hdac-9; histone deacetylase 4/5-related protein; Histone deacetylase 7B; Histone deacetylase 9; Histone deacetylase-related protein; MEF-2 interacting transcription repressor (MITR) protein; MEF2-interacting transcription repressor MITR 基因别名: HD7; HD7b; HD...
HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Mutations to the HDAC4 gene have been found in Brachydactyly-...
HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Mutations to the HDAC4 gene have been found in Brachydactyly-...
蛋白别名:DKFZp779K1053; HD7; HD9; hdac-9; histone deacetylase 4/5-related protein; Histone deacetylase 7B; Histone deacetylase 9; Histone deacetylase-related protein; MEF-2 interacting transcription repressor (MITR) protein; MEF2-interacting transcription repressor MITR ...
The MA5-17119 immunogen is purified recombinant fragment of human MEF2C (amino acids: 1-125) expressed in E. Coli. MA5-17119 detects MEF2C which has a predicted molecular weight of approximately 51.2kDa. 靶标信息 MEF2C is a transcription activator which binds specifically to the MEF2 element...