S RdjerB SwolinJ WestinJohn Wiley & Sons, Ltd.Acta Medica ScandinavicaRodjer S, Swolin B, Westin J: Monoclonal gammopathy —a diagnostic challenge. Illustrated by four cases of multiple myeloma with an unusually indolent ( smoldering) course . Acta Med Scand 1983, 214 :325–329....
The finding of an IgM monoclonal gammopathy often represents a diagnostic challenge. In fact, there are many pathological disorders associated with this condition, each of which has distinctive characteristics and requires specific clinical, instrumental, and laboratory assessments to set the appropriate ...
MonoclonalGammopathyofUndetermined Significance(MGUS)and SmolderingMultipleMyeloma(SMM) Objectives •Definition •Diagnosticcriteria •EtiologyandPathogenesis •Diagnosticwork-up •Prognosticfactors •Patientmanagement Definition MGUSandSMMareasymptomaticplasmacellsdisordersthatareassociatedwithariskof progression...
Before proceeding to treatment selection for multiple myeloma, it is important to exclude monoclonal gammopathy of unknown significance or any similar smou... L Camba,PBGM Durie - 《Drugs》 被引量: 3发表: 1992年 Comparision of the diagnostic sensitivity of biochemical tests in the screening of ...
The term monoclonal gammopathy of renal significance (MGRS) was introduced by the International Kidney and Monoclonal Gammopathy Research Group (IKMG) in 2012. The IKMG met in April 2017 to refine the definition of MGRS and to update the diagnostic criteria for MGRS-related diseases. Accordingly,...
Clinical Epidemiology 26 August 2013 Number of times this article has been viewed Objective: To estimate the positive predictive value (PPV) and completeness of the monoclo- nal gammopathy of undetermined significance (MGUS) diagnosis coding in a hospital registry within a population-based health-care...
Oncogenic drivers of progression of monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) such as c-MYC have downstream effects on intracellular metabolic pathways of clonal plasma cells (PCs). Thus, extracellular environments such as the bone marrow (BM) plasma likely ha...
PCD, plasma cell dyscrasia; MGUS, monoclonal gammopathy of undetermined significance. 1. Multiple myeloma 2. PCD 3. Monoclonal gammopathy of undetermined significance (MGUS) The diagnostic criteria for each of these three clinical entities have been published by the International Myeloma Wor...
Radiation exposure is a possible predisposing factor for monoclonal gammopathy of undetermined significance (MGUS), but the association has been uncertain. We investigated the relationship between radiation exposure and MGUS prevalence by using data from the M-protein screening for Nagasaki atomic bomb sur...
1.Kyle RA, Durie BG, Rajkumar SV, Landgren O, Blade J, Merlini G, et al. Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asyntomatic) multiple myeloma: IMWG consensus perspectives risk factors progression and guidelines for monitoring and management. Leukemia 2010;24:1121...