Quantitative measurement of serum monoclonal component (MC) is one of the most important and valuable tools for diagnosis and monitoring disease activity in monoclonal gammopathies. We have developed a standardized procedure to quantify the MC in compliance with recommendations from the International ...
Monoclonal gammopathies are disorders characterized by the proliferation of a single clone of plasma cells producing a homogeneous monoclonal protein (M-protein, M-component, paraprotein). Each M-protein consists of two heavy polypeptide... Robert,A.,Kyle,... - 《Hematology/oncology Clinics of No...
Human plasma P component (protein AP): changes during growth and development and evidence for hepatocellular synthesis no difference in the mean level of 23 patients on warfarin or 16 patients with plasma cell dyscrasia or chronic lymphocytic leukemia, and a depression ... AR Thompson - 《...
上海玉博生物科技有限公司 主要致力于“PIERCEMA112584Anti-Exosome component 1 Monoclonal Antibody100 µg 100 µg”的生产销售。多年的“PIERCEMA112584Anti-Exosome component 1 Monoclonal Antibody100 µg 100 µg”生产与销售的经验,与各行业新老用户建立
Muromonab-CD3, the first monoclonal antibody to be approved for human use (in 1986), is a mouse MAb that reacts with CD3, a component of the TCR complex (see Fig. 35-4). Antibody binding induces internalization of the TCR. Sensitive T cells die in response to complement activation; othe...
The linker component of antibody-drug conjugates (ADC) is a key feature in developing optimized therapeutic agents that are highly active at well tolerated... SC Alley,DR Benjamin,SC Jeffrey,... - 《Bioconjug Chem》 被引量: 320发表: 2008年 Association between Randall's plaque and calcifying ...
In the presence of Ca2+, Calumenin interacts with serum amyloid P component (SAP) and, together, they may play a role in the immunological defense system and participate in amyloidosis, the pathological formation of amyloid deposits in different types of tissues. Calumenin has an inhibitory effect...
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer com...
Monoclonal antibodies (IG1, k) directed against a surface component of Plasmodium berghei sporozoites (Pb-44) confer complete protection to mice against a lethal inoculum of parasites. The degree of protection is a function of the number of parasites used in the challenge and of the antibody co...
Genes such as cyclin D1 and c-myc are activated following the molecular interaction between β-catenin and lymphoid enhancer binding factor (LEF)/T-cell factor in the nucleus (TCF)25. We have already demonstrated that (P)RR is an important component of the canonical Wnt signaling pathway in...