According to the literature this antibody recognizes the CD34 antigen. Each lot of this antibody is tested by flow cytometry using the KG-1a cell line and provides a minimum of 100 tests. For APC conjugates: excitation 600-650 nm/peak emission 660 nm. Matching isotype control is available: ...
Description: The RAM34 monoclonal antibody reacts with mouse CD34, also known as mucosialin. It has been reported that the RAM34 antibody can be used to detect CD34+Sca-1+c-Kit+ cells. CD34 is a highly glycosylated (approximately 90-120 kDa) member of the sialomucin family and is expres...
抗原:CD34 物种:人 宿主:小鼠 抗体亚型:IgG 克隆号:4H11 荧光染料:PE 产品介绍 技术参数 相关产品 产品介绍 抗体类型: 单抗 同型对照: IgG1, kappa 免疫原性: 用法: 5 µL (0.5 µg)/test(flow) Description: The 4H11 monoclonal antibody reacts with human CD34, also known as mucosialin. CD34...
Podocalyxin (gene name PODXL) is a CD34-related sialomucin implicated in the regulation of cell adhesion, migration and polarity. Upregulated expression of podocalyxin is linked to poor patient survival in epithelial cancers. However, it is not known if podocalyxin has a functional role in tumor ...
This review will focus on three major aspects of monoclonal antibody therapy: 1) new therapeutic approaches with currently approved agents; 2) preclinical and clinical experience accumulated on new agents in the last few years; discussion will include available phase I, II, and III data on ...
et al. The monoclonal anti-VLA-4 antibody natalizumab mobilizes CD34+ hematopoietic progenitor cells in humans. Blood 111, 3893–3895 (2008). Article CAS PubMed Google Scholar Aksoy, S. et al. Rituximab-related viral infections in lymphoma patients. Leuk. Lymphoma 48, 1307–1312 (2007). ...
Using in vitro functional assays, we found that this antibody can be used to sort a CD34+CD38−CD110+ population enriched in hematopoietic progenitor stem cells, both in CB and in adult BM. In vivo injection into NSG mice further indicated that the CB CD34+CD38−CD110+ population is ...
Anti-CD48 mAb doesn’t damage CD34+ HSCs/HPCs. From the data, we learn that the CD48 is a novel molecular target for antibody therapy in multiple myeloma. For any additional assistance, please feel free to reach out to our scientists. Program...
Different behaviour of fresh and cultured CD34+ cells during immunomagnetic separation. "MHCD3801 was used in flow cytometry to characterize CD34+ cells derived from human cord blood after culture." 5.Photochemistry and photobiology Characterization of endogenous protoporphyrin IX induced by delta-aminolevu...
The antibody decreased proliferation of the primary T-ALL cells and depleted leukemia initiating CD34/ CD44 high population. At relatively high concentrations, (10–20 μg/ml), the MAb affected Notch1 signaling in the breast and colon cancer cell lines. The Notch-high cells sorted from solid...