This antibody has specificity for Mouse Endoglin/CD105/ENG. 靶标信息 CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated ...
www.nature.com/scientificreports OPEN Monoclonal antibody with conformational specificity for a toxic conformer of amyloid β42 received: 29 February 2016 and its application toward theaccepted:14June2016 Published:04July2016 Alzheimer's disease diagnosis Kazuma Murakami1, Maki Tokuda1, Takashi ...
Crimean-Congo hemorrhagic fever virus (CCHFV) is a WHO priority pathogen. Antibody-based medical countermeasures offer an important strategy to mitigate severe disease caused by CCHFV. Most efforts have focused on targeting the viral glycoproteins. Howev
Initially, the antibody DNA sequences are assembled into a library. The variable regions (VH and VL) are the only areas where antibody variability is present. These gene segments are put into a particular vector such that the sequence encoding the phage protein pIII is in a frame. Eventually,...
In the 1980s early investigation with murine monoclonal antibodies in animal models and patients established most of the principles of antibody therapy including immunologic and regulatory mechanisms of anti-cancer effects, and the use of immunoconjugates in which antibodies act as carriers. These early...
Antibody HostMouse IsotypeIgG1 ClonalityMonoclonal ImmunogenHuman tonsillar B cells SpecificityThis antibody detects CD180. BufferPBS with 15 mM sodium azide, approx. pH 7.4 State: Aff - Purified State: Liquid Ig fraction Concentrationlot specific ...
Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 1975;256:495–7. Article PubMed Google Scholar Buss NAPS, Henderson SJ, McFarlane M, Shenton JM, De Haan L. Monoclonal antibody therapeutics: history and future. Curr Opin Pharmacol. 2012;12:615–22. ...
Antibody 克隆号 F11 抗原 Human CD61. 偶联物 PE 激发/发射光谱 565/576 nm 查看光谱 形式 Liquid 浓度 0.1 mg/mL 纯化类型 purified 保存液 PBS with BSA, sucrose 内含物 0.1% sodium azide 保存条件 4° C 运输条件 Ambient (domestic); Wet ice (international) RR...
Nanoparticles can also be functionalized with targeting ligands to further improve their specificity and modify localization such as increasing accumulation in lymph nodes. For example, Abdi and colleagues tethered a MECA79 antibody, which recognizes peripheral lymph node addressin molecules expressed ...
(CDRS) and four frameworks. The CDR forms a complementary steric structure with the antigen molecule and determines the specificity of the antibody. The three CDRs inserted between the four framework regions (FRs) are present like a mosaic in the variable region (E. A. Kabat et al., ...