HumansMiceProstateProstatic NeoplasmsGlycoproteinsAntibodies, MonoclonalAntigensAntigens, NeoplasmEpitopesHybridoma culture F5 has been developed which secretes monoclonal antibody (McAb) directed to an of a prostatic of Mr 34 kD (Prostate Antigen, PA). Tissue levels of PA have been evaluated using a...
humans (Presta, 2006) and the production of human antimouse antibodies. This adverse immune reaction tomonoclonal antibody therapyled to quick neutralization and clearance of the murine antibody from the blood circulation, leading to poor efficacy and systemic toxicity in recipient patients. Moreover,...
These early studies also showed that most of the toxicities associated with monoclonal antibodies relate to the target antigen, and less often immune interactions with the antibody itself. In 1997 the United States Food and Drug Administration approved rituximab (Rituxan) for the treatment of B-cell...
Anti-hDectin-1-IgG (clone 22H8) is a monoclonal mouse IgG isotype 1 antibody specific for human Dectin-1. Application: Detection and neutralization of human Dectin-1-induced cellular activation Specificity: human Dectin-1
Therefore, we moved to MAb1.6.1 monoclonal antibody, described as being suitable for CD110 FACS detection [13]. When tested on the different cell lines, this antibody gave a low-intensity signal on both HL-60- and K-562-negative cells (Fig. 1A), but allowed unambiguous detection of CD...
Not for any clinical, therapeutic, or diagnostic use in humans or animals. Background CD79 (Cluster of Differentiation 79) is a transmembrane protein that forms a complex with the B-cell receptor (BCR) and generates a signal following recognition of antigen by the BCR. We can offer labeled ...
Antibody 克隆号 22URTI 偶联物 PE Request custom conjugation 激发/发射光谱 565/576 nm查看光谱 形式 Liquid 浓度 5 µL/Test 纯化类型 Affinity chromatography 保存液 PBS, pH 7.2, with BSA 内含物 0.09% sodium azide 保存条件 4°C, store in dark, DO NOT FREEZE!
An affinity-matured human monoclonal antibody targeting fusion loop epitope of dengue virus with in vivo therapeutic potency Article Open access 21 June 2021 Data availability The crystal structures of Gn complexed with the Fab form of the monoclonal antibodies R12, R13 and R15 and the scFv of...
In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis. 仅用于科研。不用于诊断过程。未经明确授权不...
5 Monoclonal antibodies can be conjugated with chemotherapy (chemolabeled, e.g., brentuximab vedotin for treatment of Hodgkin lymphoma), or conjugated with radioactive particles (radiolabeled antibody, e.g., britumomab tiuxetan for treatment of non-Hodgkin lymphoma). Conjugated antibodies could be ...