The present invention provides a useful as therapeutic and / or prophylactic expression of cell-associated disease GT468 antibody therapeutic agent, the disease including tumor-related diseases such as breast cancer, lung cancer, stomach cancer, ovarian cancer, and hepatocellular carcinoma.乌尔·沙欣...
Monoclonal Antibodies for Cancer Immunotherapy Monoclonal antibody for cancer immunotherapy has become established over the past 15 years and is now one of the most successful and important strategies for treating patients with haematological malignancies and solid tumours. Monoclonal antibody functions in ca...
Antibodies are important therapeutic agents for cancer. Recently, it has become clear that antibodies possess several clinically relevant mechanisms of action. Many clinically useful antibodies can manipulate tumour-related signalling. In addition, antibodies exhibit various immunomodulatory properties and, by...
Monoclonal antibodies (mAbs) that regulate the immune response are now being clinically evaluated as anticancer agents. This Review discusses their progress to date and the possibilities for combining these antibodies with other cancer treatments. Increa
Enter monoclonal antibodies, hailed as the vanguard of this medical revolution. These specialized proteins, designed to target specific molecules within cancer cells, are offering new avenues for treatment. From breast cancer to lymphoma, f...
Monoclonal Antibody Therapy is a cancer treatment that utilizes antibodies to target tumor cells and stimulate the immune system for long-lasting responses. AI generated definition based on: Methods in Cell Biology, 2023 About this pageSet alert Also in subject areas: Agricultural and Biological Scien...
Monoclonal antibodies like cetuximab bind to proteins on the surface of cancer cells, halting their growth and proliferation. In contrast, durvalumab, animmune checkpoint inhibitor, blocks a protein on cancer cells called PDL1, which allows tumors to thrive, allowing the immune system's T cells to...
In summary, we identified FABP4 as a new adipokine promoting breast cancer development and developed the first humanized anti-FABP4 monoclonal antibodies for treating breast cancer in mouse models. Blocking circulating FABP4 with monoclonal antibodies might represent a novel therapeutic strategy for treat...
Colorectal cancer; mAbs: Monoclonal antibodies CAR-T cells: Chimeric antigen receptor T cells TAAs: Tumor-associated antigens TME: Tumor microenvironment VEGF: Vascular endothelial growth factor EGFR: Epidermal growth factor receptor IGF-1R: Insulin-like growth factor 1 receptor HER2/neu: ...
Treating women with early-stage breast cancer with the monoclonal antibody trastuzumab after surgery reduces the risk of cancer recurrence. Treating women diagnosed with one type of early-stage breast cancer with the monoclonal antibody trastuzumab after surgery reduces the risk of the cancer ret...