Bispecificmonoclonal antibodies (bsMAb) are versatile, and can increase the specificity andsensitivity of detection in the suspected individuals. Therefore, immunodiagnostic assaysusing bsMAb are less expensive, and a large number of clinical samples could be analyzed ata faster rate for the detection ...
Monoclonal antibodies are increasingly used to prevent and treat viral infections and are pivotal in pandemic response efforts. Antibody-secreting cells (ASCs; plasma cells and plasmablasts) are an excellent source of high-affinity antibodies with therapeutic potential. Current methods to study antigen-...
However, administration of mAbs carries the risk of immune reactions such as acute anaphylaxis, serum sickness and the generation of antibodies. In addition, there are numerous adverse effects of mAbs that are related to their specific targets, including infections and cancer, autoimmune disease, and...
The purpose of this study is to examine the research structure and current trends of monoclonal antibodies (mAbs) against AS from a bibliometric perspective, since the development of these drugs is currently booming. This study collected articles and reviews on mAbs against AS from the Web of ...
Human IgG1 monoclonal antibodies expressed in CHO cells that target the N- and C-half portions of CTGF, respectively, were used to assay for CTGF forms having an intact hinge region connecting the two halves of CTGF. The N-half-reactive antibody binds to Domain 1 of CTGF and is referred ...
The testicular parenchyma is a tissue with positive reactivity for immunohistochemicalcontrol. With immunohistochemistry a differentiation of the specific antigens which are based on the reaction antigen-antibody is realised.The monoclonal antibodies are produced by a single clone of plasmocites ,being iden...
The coronavirus disease 2019 (COVID-19) pandemic is an exceptional public health crisis that demands the timely creation of new therapeutics and viral detection. Owing to their high specificity and reliability, monoclonal antibodies (mAbs) have emerged a
Monoclonal antibodies in immunodiagnosis and immunotherapyRavindranath MH, Terasaki PI, Pham T, Jucaud V. The Monospecificity of Novel Anti-HLA-E Monoclonal... OB Terasakifoundationlaboratory - 《Monoclonal Antibodies in Immunodiagnosis & Immunotherapy》 被引量: 0发表: 2015年 Production and characteriza...
Recombinant antibodies are becoming the affinity reagent of choice for use in various laboratory and clinical research applications due to consistency in performance across lots and the ability to express indefinitely in well-defined mamm...
One successful approach to disable erbB receptors was the development of the therapeutic monoclonal antibody Herceptin, which is a product of research begun in the early 1980s. This review will focus on the development of monoclonal antibodies able to inhibit or eradicate tumor cells, their ...