Monoamine oxidase (MAO) is an enzyme of the outer mitochondrial membrane that occurs in a variety of tissues, including the heart, the liver, kidneys, the spleen, platelets, the peripheral nervous system, and the central nervous system. MAO inhibitors prevent the action of MAO〢, MAO〣, or ...
Monoamine oxidase inhibitor:One of a potent class of medications used to treat depression. AbbreviatedMAOI. From Depression Resources Depression Patient Blogs Advances in Treatment for Depression Featured Centers What Are the Best PsA Treatments for You?
Monoamine Oxidase Inhibitors Themonoamine oxidaseenzyme system is responsible for the metabolic breakdown ofbiogenic amines, such as NE, epinephrine, serotonin, and DA. This class of antidepressant is a nonselective, irreversible inhibitor of the monoamine oxidase enzyme, resulting in increased concentr...
monoamine oxidase inhibitor- any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate MAOI antidepressant,antidepressant drug- any of a class of drugs used to treat depression; often have undesirable side effects ...
isocarboxazid, nialamide, phenelzine, and tranylcypromine are nonselective monoamine oxidase inhibitors. Clorgyline, moclobemide, and toloxatone are type A monoamine oxidase inhibitors whereas selegiline is a type B monoamine oxidase inhibitor. The type B receptors are less commonly found in the al...
Monoamine oxidases (MAOs) are flavoproteins of the outer mitochondrial membrane that catalyze the oxidative deamination of biogenic and xenobiotic amines.
1.Products with pseudoephedrine should not be used while taking, or within two weeks of stopping, a prescription monoamine oxidase inhibitor, which is most commonly used to treat for depression or Parkinson’s disease. 2.The medications work on an enzyme, monoamine oxidase, that boost levels of...
Linezolid is an oxazolidinone antibiotic with weak monoamine oxidase (MAO) type A and MAO type B inhibitory effects. Linezolid has been associated with serotonin toxicity when used concomitantly with multiple medications that are known to increase serotonin concentrations. We report the case of a 65-...
Monoamine oxidase A: pharmacodynamics in humans of moclobemide, a reversible and selective inhibitor. Br J Clin Pharmac 37: 433–439. Kegeles LS, Slifstein M, Frankle WG, Xu X, Hackett E, Bae SA et al (2008). Dose-occupancy study of striatal and extrastriatal dopa- mine D2 receptors...
Brain monoamine oxidase A binding in major depressive disorder: relationship to selective serotonin reuptake inhibitor treatment, recovery, and recurrence. Arch Gen Psychiatry 66: 1304–1312. Moses-Kolko E, Wisner K, Berga S, Grace A, Price JC, Mathis C et al (2005). [C-11]raclopride-PET...