The monoamine oxidase inhibitors (MAOIs) have been in clinical use for five decades. The coincidental discovery that inhibiting brain monoamine oxidase resulted in antidepressant benefits indirectly led to the norepinephrine (NE) and serotonin hypotheses for depression. Phenelzine (PLZ) and tranylcypromine...
monoamine oxidase inhibitor n.Abbr.MAOI Any of a class of antidepressant drugs that block the action of monoamine oxidase in the brain, thereby allowing the accumulation of monoamine neurotransmitters such as norepinephrine and serotonin. American Heritage® Dictionary of the English Language, Fifth Ed...
While the classical, nonselective and nonreversible MAOIs, such as phenelzine and tranylcypromine, are characterised by the risk of inducing a hypertensive crisis when dietary tyramine is ingested, the selective monoamine oxidase-B (MAO-B) inhibitor selegiline (deprenyl) and, even more so, the ...
Monoamine Oxidase Inhibitors Themonoamine oxidaseenzyme system is responsible for the metabolic breakdown ofbiogenic amines, such as NE, epinephrine, serotonin, and DA. This class of antidepressant is a nonselective, irreversible inhibitor of the monoamine oxidase enzyme, resulting in increased concentr...
Monoamine oxidase inhibitor:One of a potent class of medications used to treat depression. AbbreviatedMAOI. From Depression Resources Depression Patient Blogs Advances in Treatment for Depression Featured Centers What Are the Best PsA Treatments for You?
A novel cholinesterase and brain-selective monoamine oxidase inhibitor for the treatment of dementia comorbid with depression and Parkinson's disease B. H. ( 2003 ) A novel cholinesterase and brain-selective monoamine oxidase inhibitor for the treatment of dementia comorbid with depression and Parkinson...
tyramine oxidase 酪胺氧化酶 相似单词 monoamine n. [化]一元胺 oxidase n. [生化]氧化酶 inhibitor n. 止氧剂抑制剂 dopa oxidase 【医】 多巴氧化酶, 二羟苯基丙氨酸氧化酶 endo oxidase 【医】 [细]胞内氧化酶 indophenol oxidase 【医】 靛酚氧化酶, 细胞色素氧化酶 urico oxidase 尿酸氧化...
Monoamine oxidases (MAOs) catalyse the oxidation of neurotransmitter amines and a wide variety of primary, secondary and tertiary amine xenobiotics, includ
Yip, The monoamine oxidase inhibitor--tyramine interaction. The Journal of Clinical Pharmacology, 1989. 29(6): p. 529-532.Brown C, Taniguchi G, Yip K (1989) The monoamine oxidase inhibitor- tyramine interaction. J Clin Pharmacol 29:529-532....
How exactly is theobromine thought to interact with monoamine oxidase? If theobromine is a competitive inhibitor of MAO, then one would expect structural similarities between theobromine and the substrates of MAO (although the structural similarities are not always obvious as is the case with some est...