In contrast, the oxi- dation of Cys-SH to Cys-SOH (sulfenic acid), Cys-SO2H (sulfinic acid) or Cys-SO3H (sulfonic acid) has not been well investigated [3]. While it is known that cysteine disulfide and Cys-SOH are reduced by glutathione and thioredoxin [4], the proteins involved in...
Eq ¼ eN T εr ε0KG ð9Þ Table 1 Typical photorefractive data for different types of photorefractive composites reported in the literature Material composition (wt%) λ (nm) I (W cm − 2) E (V μm − 1) η/ηext (%) τ/τ − 1(ms/s − 1) S (cm2 J − 1...
Self-supporting composite buckypapers containing 50 wt% multi-wall carbon nanotubes (MWCNTs) and SnOx or VOx were prepared by filtration using two different methods. Either the metal-oxides were pre-prepared and mixed with the nanotubes only before filtration (co-filtration method), or the MWCNTs...
This pattern parallels the developmental expression of somatostatin immunoreactivity. The expression of somatostatin-immunoreactive peptide products using gel filtration chromatography was determined over the same period. Three molecular weight forms occur during development: a high m.wt. product and two ...
Adenosine receptors, G protein–coupled receptors (GPCRs) that are activated by the endogenous ligand adenosine, have been considered potential therap
为了进一步证实过氧化的PRDX3通过抑制胱氨酸的吸收而促进铁死亡,作者比较了PRDX3-/-和WT细胞在胱氨酸贫化培养基中的存活率,这种培养基不能为胱氨酸的吸收提供细胞外来源。即使WT细胞在胱氨酸饥饿时产生了过氧化的PRDX3,PRDX3-/-和WT细胞在此条件下对铁死亡同样敏感,铁死亡可被铁氧化抑制剂deferoxamine或ferrostatin-1...
SOLUTION: This composition comprises (A) 1-50 pts.wt. of an polyalkyl ether/polyaryl ether sulfone copolymer which is composed of repeating units of (i) the formula -Ar1-X-Ar2-O-, (ii) the formula -Ar3-Y-Ar4- and (iii) the formula (-RO-)k, [X is SO2; Ar1 to Ar4 are ...
T. Molecular basis for the resistance of human mitochondrial 2-Cys peroxiredoxin 3 to hyperoxidation. J. Biol. Chem. 288:29714-29723; 2013.Haynes AC, Qian J, Reisz JA, Furdui CM, & Lowther WT (2013) Molecular basis for the resistance of human mitochondrial 2-Cys peroxiredoxin 3 to hyper...
Clinical data for patients with premature pubarche or hirsutism with hormonal evidence of decreased adrenal 3P-HSD activity Patient At initial evaluation of ACTH stimulation test Age Sex (y) Ht: cm (Ht age) Wt: kg ( ~ agt e) EthnicityIRace Pubarchal age (y) Childhood growth acceleration ...
Fig. 4. (A) Structure of BRD9876; (B) Structure of ispinesib; (C) The degree of influence of WT, D30V and Y104C on the activity of BRD9876 and ispinesib. This figure is adapted from Chattopadhyay et al. [36]. Dihydropyrimidine derivatives are kinesin spindle (KSP) inhibitors can...