Major depressive disorder (MDD) is a psychiatric disease of still poorly understood molecular etiology. Extensive studies at different molecular levels point to a high complexity of numerous interrelated pathways as the underpinnings of depression. Major systems under consideration include monoamines, stress...
Esler WP, Kimberly WT, Ostaszewski BL, Diehl TS, Moore CL, Tsai JY, Rahmati T, Xia W, Selkoe DJ, Wolfe MS (2000) Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1. Nat Cell Biol 2:428–434 Article PubMed CAS Google Scholar Espeland MA, Rapp SR...
After littermate interacting trial, the obviously increased c-Fos expressions in CA1 and CA3 regions of wild-type (WT) mice were eliminated in Lnx1−/− mice, while the invariant c-Fos+ cells in WT DG area were increased in Lnx1−/− mice, and the other regions remained unchanged...
Interestingly, the nsP1-m7GMP structure was obtained when we incubated nsP1 with a 12-mer RNA from the 5′ end of the CHIKV viral genome with a Cap-0 structure at the 5′ end (m7GpppAUGGCUGCGUGA, hereafter named m7GpppAU-10). This indicates that wild-type (WT) nsP1 can cleave ...
Angiogenesis, the process of new capillary formation from a pre-existing vessel plays an essential role in both embryonic and postnatal development, in the remodeling of various organ systems, and in several pathologies, particularly cancer. In the last
The novelty of this work is that the different volume fractions of 0.2 – 1 wt% of MWCNT were dispersed to study the contact angle, viscosity and thermal conductivity of the prepared molecular liquid and then, the potential of MWCNT suspended in vegetable oil is used to evaluate the outcomes...
The objective was to study the promotional effect of the addition of different CeO2 contents and 15 wt% La2O3 on the stability of Rh/-Al2O3 catalysts for ethanol steam reforming reaction. The physico-chemical characteristics of the catalysts, activity and the deposition of carbon on the ...
Seinost G, Golde WT, Berger BW, Dunn JJ, Qiu D, Dunkin DS, Dykhuizen DE, Luft BJ, Dattwyler RJ: Infection with multiple strains of Borrelia burgdorferi sensu stricto in patients with Lyme disease. Arch Dermatol. 1999, 135 (11): 1329-1333. 10.1001/archderm.135.11.1329. PubMed CAS Goo...
The effect of D-AP5 on IPSC amplitude was compared in mice with GluN1 expression intact (black; PV-WT::GluN1fl/fl) or GluN1 knocked out (pink; PV-Cre::GluN1fl/fl) from PV+ interneurons. b Representative recordings of feedforward IPSCs in slices from PV-WT::GluN1fl/fl (left) ...
(2004). The 70 kilodalton heat shock protein is an inhibitor of apoptosis in prostate cancer. Int J Hyperthermia 20: 835–849. Article CAS PubMed Google Scholar Kalinowska M, Garncarz W, Pietrowska M, Garrard WT, Widlak P . (2005). Regulation of the human apoptotic DNase/RNase ...