1. Evolution of molecular weight (A) and the normalized spacial score (B) for 1916 approved drugs based on the first date of approval using data extracted from DrugCentral. We also examine the relationship between MC and two critical SMD properties target bioactivity and oral bioavailability (Fig...
46, and was recently shown to be required for BREX defense43. We studied how the presence of SAM affects DNA binding by BrxX (Fig.1C). BrxX non-specifically bound the 43 bp dsDNA probe with low affinity. The binding was improved...
the renin genes of human [1–4], mouse [5–10] and rat [11,12] have been isolated and sequenced, together with complementary (c)DNAs of mouse [1,5,13-16], human [17,18], rat [11] and sheep [19]. This has revealed not only the structure of the coding nucleotides...
In addition, many of APOBECs form functionally relevant high molecular weight homo-and hetero complexes which are required for their catalytic activity. For example, APOBEC1 forms complex with APOBEC1 complementation factor (A1CF) which is an RNA binding protein co-factor, AID is functionally ...
Plant-deleterious microbial volatiles activate the transactivation of hypoxia, MAMPs and wound responsive genes in Arabidopsis thaliana. AtMKK1 and AtMKK3
Kockx, G. Dubois, B. Laine, et al. Negative regulation of human fibrinogen gene expression by peroxisome proliferator-activated receptor alpha agonists via inhibition of CCAAT box/enhancer-binding protein beta J Biol Chem, 276 (2001), pp. 33471-33477 View PDFView articleView in ScopusGoogle ...
10.1093/nar/gkx1037 View at publisherCrossrefView in ScopusGoogle Scholar 28. Scott K. A., Ropek N., Melillo B., Schreiber S. L., Cravatt B. F., Vinogradova E. V. Stereochemical diversity as a source of discovery in chemical biology Curr. Res. Chem. Biol., 2 (2022), p. 10.10...
International Journal of Molecular Sciences Article Cellular Localization of Wheat High Molecular Weight Glutenin Subunits in Transgenic Rice Grain Yeong-Min Jo 1,†, Kyoungwon Cho 1,2,†, Hye-Jung Lee 1,3, Sun-Hyung Lim 1, Jin Sun Kim 1, Young-Mi Kim 1,* and Jong-Yeol Lee 1,* ...
NGS short reads were mapped to the CAstV isolate CkP5 (GenBank accession# KX397576), under App Map function of CLC Genomics Workbench v 12.0.2 (Qiagen, Valencia, CA, USA) using default settings. Whole genome sequences were aligned using MAFFT v7.450 [34,35], and phylogenetic trees were...