B. Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids. Proc. Natl Acad. Sci. USA 97, 9573–9578 (2000). Article CAS PubMed PubMed Central Google Scholar Lee, I. H., Li, W. P., Hisert, K. B. & Ivashkiv, L. B. Inhibition of interleukin 2 signaling and signal ...
HER2 has been used as a target to develop breast cancer vaccines. Due to its large molecular weight, vaccines have been generated by targeting HER2 based on one or more HER2-derived peptides. E75 or nelipepimut-S is a peptide-based vaccine that targets HLA-A2-restricted nonapeptide derived ...
Molecular dynamic results show that a cluster of IL is first formed in each extraction process, and NA molecules are deposited on its surface. Different outcomes are obtained for diffusion coefficient values and radial distribution function. Furthermore, the quantum chemistry calculations show that a ...
organic solvent nanofiltration2,3and crude oil fractionation4,5. Nevertheless, direct evidence of subnanometre pores and a feasible method of manipulating their size is still challenging because of the molecular fluctuations of poorly defined voids in polymers6. Macrocycles with intrinsic cavities could p...
其中提取出现频率≥14次的药材,得到熟地黄、牡丹皮、当归、茯苓、金银花、山药、知母等药材,见表1。7味药材通过TCMSP、BATMAN-TCM和TCMIP数据库得到1 238个化学成分,见表2。通过ADME和Lipinski规则筛选得到43个活性成分,见表3。 Table 1 Frequency of traditional Chinese medicine prescriptions for periodontitis...
ANCOVA included covariates sex, BMI, gestational weight gain, principal component factor 1 (birthweight and gestational age) and principal component factor 2 (parental ages and durations of education), with Sidak correction for multiple comparisons. Values that do not share a letter differ ...
In order to overcome the difficulty of the determination of the molecular weight of a polymer in the low molecular weight region by viscometry using the Mark-Houwink-Sakurada (MHS) equation, we have proposed the Dondos-Benoit relationship []-1 = A 2 + AM -1/2, for a number of polymer...
2. Fig. 2 The total ion chromatograms of YZHG solution in negative (A) and positive (B) ion mode Full size image Pharmacodynamics analysis of YZHG in the treatment of ALD Effects of YZHG on body weight and organ index As shown in Fig. 3A, the bodyweight of mice in the M group ...
The influence of a high intensity physical activity intervention on a selection of health related outcomes: an ecological approach (HDL), high-sensitivity C-reactive protein (hs-CRP), fibrinogen (Fg), interleukin-6 (IL-6), adiponectin (high molecular weight), triglyceride and ... DS Buchan,S...
response regulator XBP1u [23]. Consequently, SPP has been observed in distinct high molecular weight protein complexes when analysed by native gel electrophoresis [18,24]. Interestingly, the other ER-localised SPP/SPPL protease, SPPL2c, is also part of a large, approximately 500 kDa protein ...