Science of the Total EnvironmentThe effect of natural organic matter polarity and molecular weight on NDMAformation from two antibiotics containing dimethylamine functional groups. Leavey-Roback S L,Krasner S W,Suffet I H M. Science of the Total Environment ....
The hydrolysis can be performed in various solvents, including water; liquid ammonia; alcohols such as methanol, ethanol, isopropanol, and t-butanol; amines such as methylamine, dimethylamine, ethylamine and the like; and hydroxy amines such as ethanolamine. However, it is much preferred to simply...
Avoiding N-nitrosodimethylamine formation in metformin pharmaceuticals by limiting dimethylamine and nitrite Int. J. Pharm., 620 (2022), Article 121740 View PDFView articleView in ScopusGoogle Scholar Schlingemann et al., 2022b J. Schlingemann, et al. The landscape of potential small and drug sub...
We first optimized protein refolding conditions for OEP21 in detergent micelles and identified the detergent lauryldimethylamine-N-oxide (LDAO), which has been previously reported to be suitable for the refolding of β-barrel membrane proteins15,16. An analysis of OEP21 in LDAO micelles by far-ul...
Formation of nitrosamines in alkaline conditions: a kinetic study of the nitrosation of linear and cyclic secondary amines by nitroalkanes A study has been made of the nitrosation of sixteen secondary amines, six alkylamines (dimethylamine, diethylamine, dipropylamine, diisopropylamine, dibutylamine, diis...
Sanford's strategy employed [Ru-MACHO-BH] and dimethylamine to give dimethylammonium dimethylcarbamate as intermediate that generates a mixture of DMF/MeOH in a one- pot procedure using a temperature ramp. In Milstein's approach, a [Ru-PNN] complex is the catalyst and CO2 is captured through...
(pKa 6.56), dimethylamine headgroup in DLin-MC3-DMA (pKa 6.44), and 2-ethylpiperidin headgroup in A18 (pH 6.6) [25,79,92]. Although the weakly acidic headgroup of the ionizable lipids is an important feature for the success of the LNP, it may also contribute to the instability ...
To a solution of the lactone (262 mg, 1.54 mmol) in methanol (9 mL) was added an excess of dimethylamine in solution in THF (4.62 mL of 2 M solution, 9.24 mmol, 6 eq). The reaction mixture was stirred at room temperature overnight. The methanol and any remaining dimethylamine were ...
Particularly useful tertiary amido amines herein include: stearamidopropyldimethylamine, stearamidopropyldiethylamine, stearamidoethyldiethylamine, stearamidoethyldimethylamine, palmitamidopropyidimethylamine, palmitamidopropyldiethylamine, palmitamidoethyidiethylamine, palmitamidoethyldimethylamine, behenamidopropyldimet...
such as metal hydroxides, and quaternary hydroxides, although tertiary amines are preferred, such as triethylamine, dimethyldodecylamine, benzyldimethylamine, and the like. Advancement of the low molecular weight epoxy resin seems to be fairly easy with tertiary amines such as triethyl amine, dimethyldod...