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Naked mole-rat (NMR), the longest-living rodent, produces very-high-molecular-mass hyaluronan (vHMM-HA), compared to other mammalian species. However, it is unclear if exceptional polymer length of vHMM-HA is important for longevity. Here, we show that v
Structure elucidation of unknown small molecules by mass spectrometry is a challenge despite advances in instrumentation. The first crucial step is to obtain correct elemental compositions. In order to automatically constrain the thousands of possible ca
Analyses on weight loss and electrochemical properties confirmed adsorption of inhibitor as a protective layer on the surface of steel. The inhibition efficiency of nanoparticles was enhanced as the concentration of inhibitors increased. The maximum inhibition efficiency for Fe3O4 (MNPs) and Fe3O4@...
Background Members of the periplasmic binding protein (PBP) superfamily utilize a highly conserved inter-domain ligand binding site that adapts to specifically bind a chemically diverse range of ligands. This paradigm of PBP ligand binding specificity was recently altered when the structure of the Ther...
In 2002, Tschopp et al. applied the term inflammasome to define a protein complex that mediated the stimulation of inflammatory caspases [17]. Inflammasomes are high molecular weight protein complexes activated through various pathogen infections [18] or cellular and physiological stresses that provoke ...
to any deleterious negative QTLs and would directly be useful to develop breeding materials. In several different instances, theO. rufipogonalleles showed the same effects in different genetic background and environment, supporting the stability of these yield QTLs. A thousand grain weight (TGW) QTL...
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Abstract Background Materials and methods Results Discussion Conclusions Availability of data and materials Abbreviations References Acknowledgments Funding Author information Ethics declarations Additional information Supplementary Information Rights and permissions About this article AdvertisementMolecular...
Background Major evolutionary transitions occur when multiple autonomous units (e.g., genes) combine to form an interdependent autonomous unit (e.g., chromosomes) capable of storing and transmitting information in a novel way [1]. Over the past four billion years a relatively small number of su...