glycol (e.g. 1,2-hexanediol) having a branched hydrocarbon group is thermally reacted with an aliph. dicarboxylic acid (e.g. succinic anhydride) having no branched hydrocarbon group to give a branched oligomer. Separately, succinic anhydride is thermally reacted with an aliph. glycol (e.g....
k. Examined how 1,6-hexanediol affects IGF2BP1 phase separation. l. RIP assay evaluated the impact of 1,6-hexanediol on IGF2BP1 and ITGB1 mRNA interaction. m. Assessed ITGB1 mRNA levels following 1,6-hexanediol treatment. n. HIC assay results showed ITGB1 expression in oral cancer versus...
M. Probing exchange kinetics and atomic resolution dynamics in high-molecular-weight complexes using dark-state exchange saturation transfer NMR spectroscopy. Nat. Protoc. 7, 1523–1533 (2012). Article CAS Google Scholar Fawzi, N. L., Ying, J., Ghirlando, R., Torchia, D. A. & Clore,...
The low-complexity domain of the RNA-binding protein FUS (FUS LC) mediates liquid−liquid phase separation (LLPS), but the interactions between the repetitive SYGQ-rich sequence of FUS LC that stabilize the liquid phase are not known in detail. By comb
Size exclusion chromatography multiangle light scattering (SEC-MALS) analysis showed that D1D2-L556S exists as a monomer with a molecular weight (MW) of 49 ± 0.01 kDa and a dimer (MW: 97.2 ± 4.4 kDa) (Figures S4A–S4D). On the other hand, the D1D2-WT and D1D2-R376C ...
the dielectric relaxation of 2-ethyl-1,3-hexanediol and glycerol polyalcohols (PA) do not conform to the general trend. Instead, the observed dielectric relaxation for these PAs correlates with a low frequency mode (slower than structural relaxation) emerging in the shear response. We interpret ...
molecular weight much larger than a dimer (Supplemen- tary information, Figure S5). Helix α0 is not involved in the dimeric interface of PYLs, therefore the introduction of the extra N-terminal fragment to PYL13 should not affect the interface between PYL13 and PYL10. Cor- roborating this...
1. A normally-solid, biodegradable, hydrolyzable polyester resin of diglycolic acid and an unhindered glycol having a molecular weight sufficiently high so as to provide a polymeric material possessing self-supporting film forming properties. 2. A self-supporting film produced from the polyester resin...
A process for preparing a mixture of polyhydroxyl compounds having low molecular weight by catalytically hydrogenating a formose mixture with hydrogen on a metal catalyst. The hydrogenation is carried
A process is disclosed for preparing mixtures of low molecular weight polyhydroxyl compounds and hydroxyaldehydes and hydroxyketones by condensing formaldehyde hydrate with itself in the presence of (