The crystal structure of the β-cyclodextrin (β-CyD) molecular complex with aspirin (acetylsalicylic acid), salicylic acid, and water, (C42H70O35)2 (C9H8O4)2 (C7H6O3) 23.3H2O, was determined by X-ray...Fumio NishiokaOsaka UniversityIsao Nakanishi...
The effect of aspirin on RBC membrane structure. The out-of-plane scattering for RBC membranes containing 1 mM, 1.5 mM, 2 mM, 2.5 mM and 3 mM ASA is shown in Fig. 4(a). The curve containing 2.5 mM ASA and the corresponding fit is shown in part (b). Data is...
It is well known empirically that aspirin crystals have a cleavage plane. The cleavage of aspirin crystals was studied from a quantum chemical point of view by using the CNDO/2 and ab initio methods. In the aspirin crystals the dimer with two hydrogen bonds through two carboxyl groups was mor...
Aspirin is sometimes prescribed as a treatment for preeclampsia, but it has been shown to not have any significant effect on sFLt1 levels [15]. It is shown that aspirin is associated with a decrease in sFLT1 expression [16, 17]. Gene expression knowledge continues to guide scientists in ...
Functional group attribution analysis and structure optimization of aqueous solubility As shown above, different substructures enable us to more precisely describe the boundary of fragments responsible for the predicted molecular property. Moreover, functional groups are predefined molecular substructures and ca...
Aspirin is currently widely used as a preventive treatment for preeclampsia, primarily acting through antiplatelet activity, inhibition of inflammation, protection of endothelial function, and reduction of the release of inflammatory factors, contributing to its therapeutic effects on preeclampsia [9]. Howev...
Structure and function of Gab2 and its role in cancer (Review) Chen‑Bo Ding, Wei‑Na Yu, Ji‑Hong Feng, Jun‑Min Luo Pages: 4007-4014 Published online on: 17 六月 2015 Review High-density lipoprotein synthesis and metabolism (Review) Lingyan Zhou, Congcong Li, Ling Gao, Aihong...
MM Alberto,J Correa-Basurto,M Bello - 《Journal of Biomolecular Structure & Dynamics》 被引量: 0发表: 2020年 The effects of nonsteroidal anti-inflammatory drugs on NF-κB and β-catenin signalling in colon cancer cells to be activated in response to NSAIDs and this activation was causally ...
The corresponding 3D structure files for proteins and small molecule compounds were downloaded from the RCSB database (https://www.rcsb.org/, accessed on March 19, 2023) and TCMSP database [32], followed by dehydration and hydrogenation before importing them into Autodock Tools (ver.1.5.6)....
It can also be used in the preparation of drugs, such as aspirin and acetaminophen. the structural formula of phenol shows the combination of a benzene ring and a hydroxyl group. The benzene ring is a ring structure composed of six carbon atoms, each of which is also connected to a ...