Title An R Package for Exploring Molecular Signatures Database Version1.0 Description The Molecular Signatures Database('MSigDB')is one of the most widely used and comprehensive databases of gene sets for performing gene set enrichment analysis<doi:10.1016/j.cels.2015.12.004>.The'msig'package ...
MolecularSignaturesDatabase(MSigDB)3.0ArthurLiberzon1,AravindSubramanian1,ReidPinchback1,HelgaThor-aldsdóttir1,PabloTamayo1andJillP.Mesirov1,*1BroadInstitute,Cambridge,MA02142,USA AssociateEditor:DrAlexBateman ABSTRACT Motivation:Well-annotatedgenesetsrepresentingtheuniverseofthebiologicalprocessesarecriticalforme...
Molecular signatures database (MSigDB) 3.0.LiberzonBroadArthurBroadSubramanianBroadAravindBroadPinchbackBroadReidBroadThorvaldsdóttirBroadHelgaBroadTamayoBroadPabloBroadEBSCO_AspBioinformatics
Molecular signatures database (MSigDB) 3.0 Contact: gsea@broadinstitute.org Liberzon,Arthur,Subramanian,... 被引量: 0发表: 0年 The Molecular Signatures Database (MSigDB) hallmark gene set collection. Through extensive automated and manual curation, Liberzon etal. provide a refined and concise collec...
Annotated lists of genes help researchers to prioritize their own lists of candidate genes and to plan follow-up studies. The Molecular Signatures Database (MSigDB) is one of the most widely used knowledge base repositories of annotated sets of genes inv
The Molecular Signatures Database (MSigDB) (Liberzon et al., 2011), originally developed for use with GSEA and now employed by many similar approaches, remains one of the largest and most popular repositories of gene sets. The latest version of MSigDB consists of seven collections C1–C7, whic...
TheMolecular Signatures Database (MSigDB)in a tidy data frame. This is the updated version of the archived repo of@stephenturner Current version:v2024.1.Hs(Aug 2024). Installation #Install devtools if you don't already have itinstall.packages("devtools")#Just get the datadevtools::install_gith...
Ranked lists were then analyzed for the enrichment of 50 hallmark gene sets (collection H) obtained from the molecular signature database msigDB, maintained by the Broad Institute, using the ‘plotEnrichment’ and ‘plotfgseaRes’ functions in fgsea and the ‘GSEA’ function in DOSE (nperm =...
et al. The molecular signatures database (MSigDB) hallmark gene set collection. Cell Syst. 1(6), 417–425 (2015). Article PubMed PubMed Central CAS Google Scholar Stelzer, G. et al. The GeneCards Suite: From gene data mining to disease genome sequence analyses. Curr. Protoc. Bioinform...
The set of genes of cell cycle-related signaling pathways in GO and KEGG and pathways were downloaded through the Molecular Signatures Database59(https://www.gsea-msigdb.org/gsea/msigdb/index.jsp) and collated to obtain 1865 cell cycle-related genes for further studies. Common immune checkpoint...