It is worth noticing that in this work the relationship between steroid properties and their action on membranes is evaluated in relation to a control membrane containing no steroid, and not relative to a cholesterol-containing lipid mixture, as is frequently employed. As mentioned, some steroids ...
ARs have been identified in a variety of cells found in bone, thus clearly identifying bone as a target tissue for androgen action. The direct effects of androgen that influence the complex processes of proliferation, differentiation, mineralization, and gene expression in the osteoblast are being ...
cellular, and molecular analyses are used to investigate sex differentiation and to infer the genetic sex of an individual. For the purposes of this review, sex determination is used to describe the genetic and environmental processes and variables...
Both elevated maternal serum estradiol in males only and low maternal serum sex hormone binding globulin in both sexes are associated with increased autism risk. Further investigation is merited to identify how steroid, metabolic, and inflammatory processes can interact to influence neurodevelopment in ...
The identification of BR-regulated genes demonstrates a genetic basis for BR mode of action with reference to their multiple effects. This review focuses on the relevance of BRs to the control of various physiological processes, BR-signalling and underlying molecular mechanisms by considering known ...
For instance, a recent study on Leptobrachium boringii using nonreference transcriptomic analyses found several processes (such as cytosolic processes and peptidase inhibitor activity) and a list of potential genes (such as insulin-like growth factor genes and sex steroid hormone-related genes) that ...
et al. Reduced levels of hsp90 compromise steroid receptor action in vivo. Nature 348, 166–168 (1990). This landmark paper provides important insight into the regulation of SHRs by HSP90 in vivo. Article CAS PubMed Google Scholar Ding, G. et al. Regulation of ubiquitin-like with ...
Role of passive diffusion, transporters, and membrane trafficking-mediated processes in cellular drug transport. Clin. Pharmacol. Ther. 101, 121–129 (2017). Article CAS PubMed Google Scholar Wadhwa, R. et al. Water extract of Ashwagandha leaves has anticancer activity: Identification of an ...
The epithelial cells of the gastrointestinal (GI) tract communicate with each other and with cells of other organs via a complex network of highly regulated movement of ions and biomolecules. The molecules ensure regulated activity of cells, tissues, and