rendered it an impossible task to carry out data sorting, analysis, and mining by manpower alone. Now, with the improvement of computing power and the refinement of models such as machine learning, big data has allowed for increasing perfection in t...
A rigorous molecular clock was aligned with the phylogenetic tree to measure the rate of viral evolution and the root-to-tip distance within strains in different years was assessed using regression curve models to determine the correlation. Results During the early period of COVID-19 control, ...
he has published a paper in the highly reputable and top journal, CELL (IF=36.21), as the first author. Taking advantage of genetic tool, Dr. Yao's lab already set up a couple of mouse models to answer key questions in development, tumor evolution, and nutritional function at molecular ...
. In animal models of DKD, enhanced mitochondrial fission in several types of renal cells has been reported to result in diminished energy production and accumulation of ROS, which further accelerate the progression of DKD (Sun et al.2008; Ayanga et al.2016). Not only mitochondrial fission has...
Instead, IDP structure is often described with reference to well-established homopolymer models16,17. However, no models exist for our dumbbell-shaped FRET construct (Fig. 1b), especially not models that are relevant in the cellular environment. We therefore wanted to create an empirical standard...
Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, 650223, Kunming, Yunnan, China Yalan Han & Xiancui Lu University of Chinese Academy of Sciences, Beijing, China ...
The selection of descriptors is key for Quantitative Structure-Activity/Property Relationship (QSAR/QSPR) models [229]. Extended similarity provides a flexible similarity calculation that can help find the normalization method, coincidence threshold, descriptors and coincidence variant that can separate the...
Instead, IDP structure is often described with reference to well-established homopolymer models16,17. However, no models exist for our dumbbell-shaped FRET construct (Fig. 1b), especially not models that are relevant in the cellular environment. We therefore wanted to create an empirical standard...
the actual number of carbohydrates in nature is probably significantly smaller. Modeling of enzyme kinetics and estimating the size and diversity of the glycome has been of considerable interest to the field of glycobiology. The first attempt to establish mathematical models of N-type glycosylation oc...
Instead, IDP structure is often described with reference to well-established homopolymer models16,17. However, no models exist for our dumbbell-shaped FRET construct (Fig. 1b), especially not models that are relevant in the cellular environment. We therefore wanted to create an empirical standard...