Dopamine D1 Receptors Are Coupled to Mechanisms of Synaptic Plasticity Addictive Drugs and Synaptic Change Learning Mechanisms in Addiction and Sensitization Abnormal Associative Learning and Compulsive Behavior Multiple Memory Systems and the Development of Addiction Future Directions for Research Acknowledgements...
Spatio-temporal mechanisms of consolidation, recall and reconsolidation in reward-related memory traceArticle Open access Published: 13 September 2024 (2024) Cite this article Download PDF You have full access to this open access article Molecular Psychiatry Submit manuscript ...
Neuroplasticity is simple as a concept, but extremely complex when it comes to its mechanisms. This review aims to bring to light an aspect about neuroplasticity that is often not given enough attention as it should, the fact that the brain’s ability to change would include its ability to ...
Tremendous strides have been made in our understanding of the neurobiological substrates of memory – the so-called memory “engram”. Here, we integrate recent progress in the engram field to illustrate how engram neurons transform across the “lifespan” of a memory — from initial memory encodi...
we describe how these changes during encoding and consolidation guide neural reactivation during retrieval, and facilitate memory recall. Fourth, we describe neurobiological mechanisms of forgetting, and how these mechanisms can counteract engram properties established during memory encoding, consolidation, and...
Moreover, we knew even less about the mechanisms of any form of memory storage. Indeed, we did not even know whether the storage mechanisms were synaptic or non-synaptic. In 1968, Alden Spencer and I were invited to write a perspective of learning for Physiological Reviews, which we ...
Memory Behavioural imprinting IMM 1. Introduction Over the past few decades, there has been substantial progress in understanding the mechanisms of learning and memory. This progress continues to depend on a combination of complementary experimental approaches on a variety of experimental animals. The do...
The widespread use of molecular dynamics (MD) simulation of biopolymers [1] has created a greater need for statistical tools to analyze atomic trajectories. A thorough analysis helps identify mechanisms responsible for biological function. Molecular conformation is represented by a vector space with dime...
which has culminated in the foundation of intelligent matter5. It has been postulated that four main functional criteria are required for the realization of intelligence in artificial matter: sensing, actuation, memory, and communication network1. These properties allow artificial matter to be classified...
Bouton ME, Maren S, McNally GP. Behavioral and neurobiological mechanisms of Pavlovian and instrumental extinction learning. Physiol Rev. 2021;101:611–81. Maren S, Phan KL, Liberzon I. The contextual brain: implications for fear conditioning, extinction and psychopathology. Nat Rev Neurosci. 2013...