Most MS data are presented in units of mass-to-charge ratio, orm/z,wheremis the molecular weight of the ion (in daltons) andzis the number of charges present on the measured molecule. For small molecules (<1000 Da) there is typically only a single charge and therefore them/zvalue is ...
Cells may die from accidental cell death (ACD) or regulated cell death (RCD). ACD is a biologically uncontrolled process, whereas RCD involves tightly structured signaling cascades and molecularly defined effector mechanisms. A growing number of novel no
P. A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry. Cell Stem Cell 16, 323–337 (2015). Article CAS PubMed PubMed Central Google Scholar Hansson, J. et al. Highly coordinated proteome dynamics during reprogramming of somatic cells ...
Cell contain diverse array of proteins with different molecular weight and isoelectric point (pI). The molecular weight and pI of protein play important role in determining the molecular biochemical function. Therefore, it was important to understand the
The effect of different parameters on the dye extraction efficiency, including pH of the solution, sorbent mass, sample volume, ultrasound frequencies, irradiation time, and type and volume of eluent, were investigated. In addition, response surface methodology (RSM) approach-based central composite ...
After the chromatographic separation step, the metabolites were analyzed using the AB Triple TOF 6600 mass spectrometer. The raw data were converted to the mzXML format using the ProteoWizard software. The peak alignment, retention time correction, and peak area extraction were performed using the MS...
Push enteroscopy was performed which revealed a circumferential fungating mass in the 4th portion of the duodenum, which was actively oozing blood and upon further investigation it appeared the mass extended to the ligament of Treitz (Figure 1). The area was biopsied and tattooed. Pathology from ...
The graphical notation used in the diagrammatic representation identifies species as shapes and reactions as arrows. A direct arrow from species A to species B indicates a reaction where A is a reactant and B is a product. Solid arrows stand for mass transfer reactions, i.e. reactions that ...
TMT-based mass spectrometry (MS)-quantified protein data have been submitted into iProX (https://www.iprox.cn) under accession codes IPX0006535000. Human Primary Cell Atlas data are obtained from the celldex package (v1.11; https://github.com/LTLA/celldex). The TCGA, METABRIC and CPTAC ...
As one of the most common metastatic sites of malignancies, bone has a unique microenvironment that allows metastatic tumor cells to grow and flourish. The fenestrated capillaries in the bone, bone matrix, and bone cells, including osteoblasts and osteoc