complexes I and III convert oxygen molecules (O2) to superoxide anion (O2−), becoming the major sources of ROS. O2.−can be converted to water (H2O) with hydrogen peroxide (H2O2) as an intermediary product
are also found accessible in the model obtained after MD. Finally, our model is also in good agreement with additional SCAM results [21] that suggested that TM3 and TM9 also contribute to the cytoplasmic portion of the pore: K190, D192, E193, G194, A196, L197, and F200 are indeed w...