Mammalian embryos exhibit sophisticated cellular patterning that is intricately orchestrated at both molecular and cellular level. It has recently become apparent that cells within the animal body display significant heterogeneity, both in terms of their cellular properties and spatial distributions. However,...
In addition to glucose, fructose is another major dietary carbohydrate in modern society that is closely linked to NAFLD/NASH development. While fructose and glucose have the same molecular formula (C6H12O6), they are metabolized by organs quite differently and have divergent effects on hepatic DNL30...
Determination of organ index The sacrificed mice were quickly dissected to remove the liver, spleen and kidney, and the fat and fascia were removed. The surface liquid was swabbed with filter paper, and the corresponding organ index was calculated. The calculation formulas: spleen index = spl...
The present invention provides a method of screening a library of peptides of formula M-G/M/V—(X)wherein n is an integer from 3 to 18, M is methionine, G is glycine, V is valine and each X, which may be the same or different, is any genetically encoded amino acid, which ...
NR Mehta,JB Jones,M Hamosh - 《Journal of Pediatric Gastroenterology & Nutrition》 被引量: 33发表: 1982年 146 A Randomized, Doubleblind Crossover Study Comparing Rhbssl (Recombinant Human Bilesaltstimulated Lipase) and Placebo Added to Infant Formula in Preterm Infants Pediatric Research publishes...
Finally, the absorbance of the supernatant (diluted 1/10) was measured at 595 nm, and a phosphate buffer solution without protein was used as a control. The following formula gives the surface hydrophobicity (BPB bound, μg): BPB bound(μg)=200μg×Acontrol-AsampleAcontrol. Raman ...
U Thadani - 《Journal of Cardiovascular Pharmacology & Therapeutics》 被引量: 63发表: 2004年 Antipsychotic drugs; schizophrenia This invention relates to compounds that are antagonists of dopamine D4 receptors having Formula I below ##STR1## This invention also relates to methods of... SA Glase...
Transcription factors are among the most attractive therapeutic targets but are considered largely ‘undruggable’ in part due to the intrinsically disordered nature of their activation domains. Here we show that the aromatic character of the activation domain of the androgen receptor, a therapeutic targ...
The computational formula of risk score is as follows. The risk score = 0.229994697234363*TOP2A + 0.124787795719623*SLC2A1 + 0.220093179394101*MMP14 + 0.0671974510904209*MBOAT2 + 0.0484008588233876*ANLN − 0.17194413420108*ECT2 + 0.0362333570976207*SLC22A3...
(Gempharmatech Co.Ltd, China). After the tumors formed, the tumor volumes were measured once a day. Tumor volume was calculated using the formula: Volume = 0.5 × Length × Width 2 (mm3). When the volume reached 200 mm3, mice in the irradiated group were exposed to X-rays (doses...