Fig. 2: Structural characterization of the PSMA/Glu-490 complex. a Molecular formula of the Glu-490. b A stereo view of the Gluo-490 inhibitor. The Fo-Fc omit map (green) is contoured at 3.0 σ and the inhibitor is shown in stick representation with atoms colored red (oxygen), blue...
5 Ethyl propanoate 105–37–3 19,019.33g Fruity 0.59 < 1 5.64 243 8 6 Ethyl hexanoate 123–66–0 55.33g Pineapple 60,701.43 36,848 137,558 403,100 59,049 > 8192 4096 7 Propyl hexanoate 626–77–7 12,800g Fruity 0.14 < 1 1 81 16 8 Butyl hexanoate 626–82–4 -h ...
The formation of compound 4 is then facilitated by a retro-1,3-dipolar cycloaddition, as illustrated in Scheme 1 and elucidated in the proposed mechanism (formula 1). Furthermore, under alkaline conditions and in the presence of water, (compound 4) undergoes hydrolytic cleavage to give (...
Following formula was used for calculation of Ulcer index (UI) [49]; UI = Area of Ulcer Area of Stomach × 100 (2) 3.13. Ex Vivo Antiplatelet Aggregation Activity The antiplatelet activity of synthesized mutual prodrugs 5a–c was investigated by following the already reported method with some...