Tuberculosis (TB) is the most common opportunistic infection in HIV-infected patients and the emergence of drug-resistant tuberculosis (DR-TB) is a growing problem in resource-limited settings (RLS). TB diagnosis in most RLS still depends on smear microscopy for acid-fast bacilli (AFB) while ...
and1.7milliondeaths•TB–HIVco-infection•Drug-resistantTB:MDR/XDR-TB(WHO)DiagnosisofTB Sputumsmearmicroscopy(fluorescentLED)-notsensitiveandspecific,5000–10000bacilli(45%-80%positivecultures) Culture-basedtests:slow-Requiredfordiagnosis/drug-susceptibilitytesting(DST);Severalweeks Phage-mediated...
Molecular diagnostic tools for tuberculosis (TB) have evolved quickly with new innovations which can provide unprecedented opportunities for the rapid, sensitive and specific diagnosis of M. tuberculosis in clinical specimens and the status of its drug sensitivity. Microscopy and culture methods can not...
The characterization of these mutations should be useful for the planning of prenatal diagnosis programmes for beta thalassaemia in other Asian Indian communities. 展开 DOI: 10.1111/j.1365-2141.1988.tb02468.x 被引量: 123 年份: 1988 收藏 引用 批量引用 报错 分享 ...
TB includes delayed diagnosis, prolonged or ineffective treatment, and person-to-person recent transmission. China is 1 of the 27 high MDR-TB burden countries. The prevalence of MDR-TB in China was 5.3% in recent years2. Although concentrated efforts to control TB has resulted in a sharp ...
The Xpert®MTB/RIF assay is a rapid molecular assay that can be used close to the point of care by operators with minimal technical expertise, enabling diagnosis of TB and simultaneous assessment of rifampicin resistance to be completed within 2 h. Moreover, this can be accomplished using ...
TB is curable if it is treated in a timely manner, so the accurate and rapid detection of TB has a critical role to play in the prevention and treatment of TB2. Currently, there are both direct and indirect methods of diagnosis of TB. Direct detection methods include microscopy, culture, ...
The experimental approaches discussed here are envisaged to be of clinical relevance for the molecular diagnosis of the Y-linked disorders. 展开 关键词: Minisatellite Gonadoblastoma Y-linked loci DNA diagnostics Turner syndrome Mutational load AZF, azoospermia factor cAMP, cyclic adenosine monophosphate ...
Early diagnosis of HIV and use of molecular Point-of-Care HIV testing as part of a comprehensive strategy to end HIV transmission According to UNAIDS1 the world is embarking on a Fast-Track strategy to end the AIDS epidemic by 2030. There is a strong global consensus that powerful tools now...
Preliminary results with an antisense riboprobe derived from this sequence showed the presence of IL-10 mRNA in sections of granulomatous tissues. 展开 关键词: detection diagnosis DNA probes schistosomiasis techniques DOI: 10.1111/j.1749-6632.2000.tb05320.x ...