RORs and REV-ERBs are known as orphan nuclear receptors; however, the subsequent identification of their endogenous ligands28,29led to the development of synthetic ligands targeting these receptors. Because the clock components can affect tumorigenesis, pharmacological modulation of the circadian clock is...
Children and adolescents and postoperative patients should eat more milk, eggs and fish, because these foods are rich in( ) Due to the structure diversity of phenolic compounds that occur in nature, they are recognized as valuable plant molecules with very important biological functions.( ) ...
Here, the authors propose an approach to optimize for a generalized wavefunction across compounds, which can help developing a foundation wavefunction model. Michael Scherbela , Leon Gerard & Philipp Grohs Article 02 January 2024 | Open Access Sub-Doppler optical-optical double-resonance ...
Thus, specially designed lipid nanoparticles for other tissues, such as tumor cells, with selective targeting, are required [14]. A profound understanding of the molecular structure and dynamics of these delivery carriers and drug-carrier and carrier-membrane interactions could potentially further ...
In contrast, the intermolecular condensations are more prominent when shorter organic pendant groups, such as methyls, are present. It is also known that reaction conditions, including the type of catalyst, temperature, concentration, and time, also affect the distribution of microstructures in a ...
[3,18,19,20,21]. Since there are tumor-ablative and function-reserving oncologic treatments, the use of phototherapies, such as photodynamic therapy (PDT) and photothermal therapy (PTT), in clinical cancer therapy offers great potential. Safe phototherapeutic compounds may be triggered by light ...
There are eight types of saponins based on their aglycons, and 68 kinds of saponins were found in Pulsatilla (Fig. 1). Among these compounds, PSA, AB4, PSD, PSE and Raddeanoside R13 have been studied extensively and showed a broad spectrum of bioactivities, such as antitumor, anti-...
(also known as a protein-based approach) and a gel-free approach (also called a peptide-based approach). The electrophoretic approach has been largely abandoned as a viable experimental strategy, although it still finds occasional use in a number of niche applications (Jorrin-Novo et al.2019)...
Brønsted basicity is a fundamental chemical property featured by several kinds of inorganic and organic compounds. In this Review, we treat a particularly high basicity resulting from the mechanical entanglement involving two or more molecular subunit
Prominent examples of phytocompounds include polyphenols, flavonoids, and carotenoids61. (b) Probiotic micro-organisms Live bacteria known as probiotics are said to have health advantages when ingested. Typically, they may be discovered in fermented foods like yogurt, kefir, and sauerkraut. Probiotics...