Ivermectin as an inhibitor of cancer stem‑like cells Guadalupe Dominguez‑Gomez, Alma Chavez‑Blanco, Jose Luis Medina‑Franco, Fernanda Saldivar‑Gonzalez, Ytzel Flores‑Torrontegui, Mandy Juarez, José Díaz‑Chávez, Aurora Gonzalez‑Fierro, Alfonso Dueñas‑González ...
Evolution of the number of total citation per document and external citation per document (i.e. journal self-citations removed) received by a journal's published documents during the three previous years. External citations are calculated by subtracting the number of self-citations from the total...
Cancer is caused by a combination of genetic and epigenetic abnormalities. Current cancer therapies are limited due to the complexity of their mechanism, underlining the need for alternative therapeutic approaches. Interestingly, combining the Clustered
and 6 years at ONYX Pharmaceuticals, Richmond, California, she moved to New York where she has been working at the Feinstein Institutes since 2001. Her work has centered on signaling molecules involved in cancer and during the last ten years it has focused on identifying new therapies for pedia...
Ovarian cancer (OvCa) is one of the deadliest gynecologic malignancies in females [1]. Like other solid tumors, cancer metastasis accounts for the great majority of cancer-associated deaths in the patients with OvCa [2]. Transcoelomic or peritoneal metastasis is the most preferential route of the...
A mechanism for hypoxia-induced inflammatory cell death in cancer We find that PTP1B and ABL1/2 reciprocally control RNF213 tyrosine phosphorylation and its oligomerization and RZ domain activation, and identify a unique PTP1B–RNF213–CYLD–SPATA2 pathway critical for the control of inflammatory ...
et al. Colony-stimulating factor 1 receptor (CSF1R) activates AKT/mTOR signaling and promotes T-cell lymphoma viability. Clin. Cancer Res. 26, 690–703 (2020). Article CAS PubMed Google Scholar Smith, A. M. et al. M-CSF increases proliferation and phagocytosis while modulating receptor ...
20 July 2022|Open Access PBK drives PARP inhibitor resistance through the TRIM37/NFκB axis in ovarian cancer Hanlin Ma ,Gonghua Qi &Beihua Kong Article 13 July 2022|Open Access MiR-1224-5p modulates osteogenesis by coordinating osteoblast/osteoclast differentiation via the Rap1 signaling target AD...
Mantle cell lymphoma (MCL) is a subtype of Non-Hodgkin lymphoma (NHL) of mature B-cells characterized by translocation, which is typically due to excess expression of Cyclin D1. Although with the progress in our knowledge of the causes for MCL and availa
The clinical response rate to immune checkpoint blockade (ICB) therapy in melanoma remains low, despite its widespread use. Circular non-coding RNAs (circRNAs) are known to play a crucial role in cancer progression and may be a key factor limiting the ef