The AAA+ATPase valosin containing protein (VCP) is essential for cell and organ homeostasis, especially in cells of the nervous system. As part of a large network, VCP collaborates with many cofactors to ensure proteostasis under normal, stress, and disease conditions. A large number of mutatio...
KR Beutner,SL Spruance,AJ Hougham,... - 《Journal of the American Academy of Dermatology》 被引量: 620发表: 1998年 Imiquimod, a Topical Immune Response Modifier, Induces Migration of Langerhans Cells1. Summary Langerhans cells are bone marrow derived dendritic cells that represent the major ant...
Inheritance based on the allele combination of multiple tumor modifier genes capable of modulate the phenotype manifestation of mutant major-cancer-predisposition genes is essential to determine the risk of cancer, and the response to drug treatment in a given individual. A tumor modifier gene may be...
ChemistrySelect, 8 (10) (2023), Article e202203704, 10.1002/slct.202203704 View in ScopusGoogle Scholar 8 K.S. Coleman, S.R. Bailey, S. Fogden, M.L.H. Green Functionalization of Single-Walled carbon nanotubes via the Bingel reaction J Am Chem Soc, 125 (29) (2003), pp. 8722-8723,...
Spruance SL,Tyring SK,Smith MH,et al.Application of a topical immune response modifier, resiquimod gel, to modify the recurrence rate of recurrent genital herpes: a pilot study.The Journal of Infectious Diseases. 2001Spruance, S. L., Tyring, S. K., Smith, M. H., and Meng, T. C. ...
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[59]Grozinger CM, Schreiber SL (2002) Deacetylase enzymes: biological functions and the use of small-molecule inhibitors. Chem Biol 9: 3–16. [60]Lee EY, Hu N, Yuan SS, Cox LA, Bradley A, et al. (1994) Dual roles of the retinoblastoma protein in cell cycle regulation and neuron dif...
KR Beutner,SL Spruance,AJ Hougham,... - 《Journal of the American Academy of Dermatology》 被引量: 620发表: 1998年 Immunomodulatory and pharmacologic properties of imiquimod. Imiquimod, an imidazoquinoline amine, is an immune response modifier recently approved for the topical treatment of external...
In the current study, we sought to determine if this single nucleotide deletion was responsible for the modifier effect associated with theDsm1locus on chromosome 5. We used B6 mice carrying a repaired (Edited)Gabra2allele (Edited/B6 mice) and crossed them with 129.Scn1a+/−mice to ascerta...
Shen J, Terry MB, Gammon MD, Gaudet MM, Teitelbaum SL, Eng SM, Sagiv SK, Neugut AI, Santella RM. IGHMBP2 Thr671Ala polymorphism might be a modifier for the effects of cigarette smoking and PAH-DNA adducts to breast cancer risk. Breast Cancer Res Treat 2006; 99:1-7....