A HEPES/MES buffer mix was used to adjust the extracellular pH in a range from pH 5.7 to 7.4. The intracellular solution for the recording pipettes contained 10 mM HEPES(KOH) pH 7.2, 10 mM BAPTA, 130 mM KCl, 6 mM MgCl2 and 5 mM Na2-ATP. To monitor the stability of channel ...
Variants in the APOE gene region may explain ethnic differences in the association of Alzheimer’s disease (AD) with ε4. Ethnic differences in allele frequencies for three APOE region SNPs (single nucleotide polymorphisms) were identified and tested for