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One-thousand cells were seeded in each well of 6-well plates for MDA-MB-231 and 500 for SUM149. The plates were kept back in the CO2incubator for nearly about 10–12 days. The media were changed every 3 days. On the last day, the media were aspirated, and the wells were washed wi...
On prolonged exposure to a pH of around 7.2, ASIC1 undergoes steady-state desensitization and becomes unavailable for activation and sodium conduction. ASIC1-evoked currents can be inhibited by small unspecific modulators such as amiloride or the amidine A-317567 (refs. 16,17). In contrast, ...
When the LoA analysis was restricted to European ethnicity, XX individuals showed prolonged ambulation of 1 year on average compared with RR, but this difference was not significant. The observation of a detrimental effect of the heterozygous, but not of the null homozygous genotype, was unexpected...
When the LoA analysis was restricted to European ethnicity, XX individuals showed prolonged ambulation of 1 year on average compared with RR, but this difference was not significant. The observation of a detrimental effect of the heterozygous, but not of the null homozygous genotype, was unexpected...