The main modifiable risk factor is hypertension because on the one hand it promotes atherosclerosis and, on the other hand, leads to deteriorative changes and constrictions of small brain vessels. Atrial fibrillation is the most significant risk factor for ischemic stroke, since it is responsible ...
Globally, hypertension occurs most frequently as a modifiable risk factor for stroke, in countries that are both developed and developing [120]. A study conducted in 2016 suggests an increased risk for CHD is associated with a genetic deficiency of SR-B1 [65]. Pearson et al. conducted a ...
Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study. Arterial thrombosis is a major clinical manifestation of the antiphospholipid syndrome, which is an autoimmune disease found mostly in young women. Althoug... RT...
Since stroke is a known risk factor for cognitive impairment, we also performed a sensitivity analysis excluding those with prevalent stroke at baseline. In the multivariable analysis for memory function, the significant predictors remained the same except for alcohol consumption which was no longer sig...
3.GrammarTo qualify or limit the meaning of. For example,summermodifiesdayin the phrasea summer day. 4.LinguisticsTo change (a vowel) by umlaut. v.intr. To be or become modified; change. [Middle Englishmodifien, from Old Frenchmodifier, from Latinmodificāre,to measure, limit:modus,measure...
highest quintile, and also influenced phenotypic severity in sarcomere variant carriers. Mendelian randomization identified diastolic blood pressure (DBP) as a key modifiable risk factor for sarcomere-negative HCM, with a one standard deviation increase in DBP increasing the HCM risk fourfold. Common ...
St-Onge M-P, Grandner MA, Brown D, et al; American Heart Association Obesity, Behavior Change, Diabetes, and Nutrition Committees of the Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascular Disease in the Young; Council on Clinical Cardiology; and Stroke Council...
by differences in PRS composition, population characteristics, and inclusion of other predictors. Outside the cancer literature, our conclusions align with a recent study of ischemic stroke, which demonstrated that the PRS is similarly or more predictive than multiple established risk factors, including...
Pathogenesis of miR-155 in AD-related modifiable risk factors. Hypertension, stroke, TBI, dyslipidemia, and depression are common AD-related modifiable risk factors. miR-155 regulates hypertension by inducing AgtR1, Cav1.2, FOXO3a, or p27. miR-155 might be involved in cerebrovascular diseases, in...
Age- and sex-specific relative risks for CHD and stroke associated with each of the five risk factors were derived from prospective data from the Asia-Pacific region. Hypertension was the leading vascular risk factor, explaining 20%–25% of all CHD and 36%–42% of all strokes in both ...