The FDA, like regulators in Europe and elsewhere, initially allowed emergency use of Moderna’s vaccine based on a study that tracked 44,000 people 18 and older for at least two months, the time period when serious side effects typically arise. That's shorter than the six months of s...
which enable delivery of the nucleoside-modified mRNA into host cells to allow expression of the SARS-CoV-2 S antigen. The vaccine elicits an immune response to the S antigen, which protects against COVID-19.
"We would expect to be addressing this gap in booster dose recommendations over the summer and into early fall," the FDA's Doran Fink told the panel.
That could resolve some logistical challenges facing the booster shot rollout. Some people do not have records of which doses they first received, health officials said, may have trouble finding their brand, or may have concerns over side effects or allergic reactions. Among them are myocarditis ...
As for all the talk about booster doses, the FDA’s licensure doesn’t cover those. The agency will decide that separately. The FDA already is allowing emergency use of a third dose of either the Pfizer or Moderna vaccine for people with severely weakened immune systems, such as organ tr...
As a result, the Stiko updated its coronavirus vaccine guidance and "recommends that people under 30 only be vaccinated with Comirnaty," the BioNTech-Pfizer jab, one day after France issued similar guidance. The advisory covers both initial inoculations and booster jabs even if the first vaccine...
Moderna's booster will come at half the dose of the original two shots. As for recipients of the single-shot J&J vaccine, a COVID-19 booster is recommended for everyone at least two months after their vaccination. That's because the J&J vaccine hasn't proved as protective as t...
Beyond the broad recommendations governing booster shots for most Americans, the CDC has also updated itsextensive guidanceover the past months detailing specific situations that might require more doses of vaccine. For example, a few millionimmunocompromisedAmericans who were allowed to...