severe acute allergic reactionfood allergyHymenoptera venom allergylatex allergyBackground; The EpiPen Jr (0.15 mg) and EpiPen (0.3 mg) auto-injectors, widely prescribed for the out-of-hospital treatment of ana
This tells immune cells to create even more cytokines. Overpopulation of cytokines affects the lining of joints, creating painful swelling, potentially leading to bone erosion and joint deformity. There are several treatments that can help ease symptoms and keep moderate to severe RA from getting...
Wedzicha JA, Agusti A, Donaldson G, Chuecos F, Lamarca R, Garcia Gil E. Effect of aclidinium bromide on exacerbations in patients with moderate-to-severe COPD: a pooled analysis of five phase III, ran- domized, placebo-controlled studies. COPD. 2016;13(6):669-676....
Furthermore, in nursing home patients with severe dementia (AD or vascular dementia (VaD)), memantine improved activities of daily living, care dependence and behavioural symptoms compared with placebo (13). For these reasons, memantine has the potential to improve the functional status of patients...
In a Phase III study, the investigational compound elinzanetant showed a statistically significant reduction in frequency of moderate to severe vasomotor symptoms.
Learn about SOTYKTU® (deucravacitinib), a first-line oral option for adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy. See Safety Info and Full Prescribing Information.
The initiation, anatomic pattern, and extent of tau spread in traumatic brain injury (TBI), and the mechanism by which TBI leads to long-term tau pathology, remain controversial. Some studies suggest that moderate to severe TBI is sufficient to promote t
To examine the current landscape of randomized controlled trials (RCTs) on non-pharmacological complementary and alternative medicine (CAM) therapies used for the management of moderate to severe traumatic brain injury (MSTBI). Recent Findings A total of 25 RCTs published between 2005 and 2022 were...
The incidence of IRR symptoms was highest during or after the first infusion (9%) and decreased with subsequent infusions (<4%). One patient had two serious IRRs, two IRRs led to a dose modification, and no IRRs were severe, ...
Patients were ⩾18 years, with moderate to severe RA for ⩾3 months. Active RA was defined by the presence of ⩾6 swollen joints (SJC) from a total of 66, ⩾8 tender joints (TJC) from a total of 68, and a C-reactive protein (CRP) level ⩾1 mg/dl or erythrocyte sedimenta...