This literature review aimed to explore factors driving the burden and costs of knee osteoarthritis in patients with moderate–severe pain and the current guideline recommendations for non-surgical management; through this, the real-world use and costs of non-surgical treatments were considered in the...
Our study describes the clinical outcome of total ankle replacement (TAR) performed in patients with moderate to severe varus deformity. Between September 2004 and September 2007, 23 ankles with a varus deformity > or = 10 degrees and 22 with neutral alignment received a TAR. Following specific ...
Objective To examine the onset and maintenance of efficacy of subcutaneous tanezumab for pain relief and functional improvement in difficult-to-treat patients with moderate-to-severe osteoarthritis (OA) in a 16-week dose-titration study (NCT02697773). Methods Patients were randomized to placebo (...
WHAT IS KNOWN AND WHAT THIS PAPER ADDS: Osteoarthritis is associated with increased mortality, particularly secondary to cardiovascular disease, with the risk for mortality proportional to the degree of disability secondary to the arthritis. This study suggests that management of hip or knee ...
Psoriasis: Targets and Therapy Dovepress open access to scientific and medical research Open Access Full Text Article Review Profile of tildrakizumab-asmn in the treatment of moderate-to-severe plaque psoriasis: evidence to date This article was published in the following Dove Press journal: ...
一般全膝关节置换术(TKA)的迹象痛苦,导致退化性关节炎,类风湿关节炎或创伤后关节炎的膝盖关节病致残。 *创伤后损失的kneejoint配置和功能。 •中度内翻,外翻,或屈曲畸形韧带结构可以返回到足够的功能和稳定性。以前不成功的单膝关节置换或其他程序的修订。铁人三项®全膝关节系统组件旨在 ...
5 The standard of care (and ultimate last resort) for severe, chronic pain in end-stage OA is Total Knee Arthroplasty (TKA).6 Recently there has been an increase in alternative, minimally invasive therapies, such as Geniculate Artery Embolization (GAE) which have shown promising results in ...
Meanwhile, high-intensity exercise reduced the expression of lncRNA H19 in cartilage, while the expression of lncRNA H19 increased after 4 weeks of moderate-intensity exercise. Conclusion High-intensity treadmill running can cause injury to the knee cartilage in C57BL/6 mice which leads to PTOA...
OP0129?Effect of low dose oral prednisolone on symptoms and systemic inflammation in older adults with moderate to severe knee osteoarthritis: A randomized placebo-controlled trial Background Osteoarthritis (OA), a common disabling condition, is the commonest type of arthritis worldwide. Knee OA is...
Referred to by Correction to: Stonehouse et al. Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial. Am J Clin Nutr 2022;116:672–85 The American Journal of Clinical Nutrition,...