AIMS. To compare the effects of moderate-intensity statin plus ezetimibe combination therapy to high-intensity statin monotherapy based on baseline low-density lipoprotein cholesterol (LDL-C) levels. METHODS AND RESULTS. In the RACING trial, 3780 atherosclerotic cardiovascular disease (ASCVD) patients ...
1 This estimate was based largely on trials of moderate-intensity statin therapy. However, high-intensity atorvastatin (80 mg) has been shown to reduce CVD events more than moderate-intensity statins (atorvastatin [10 mg], pravastatin [40 mg], or simvastatin [20-40 mg]) in individuals with ...
In absolute terms, there were 2.0 additional cases of diabetes per 1000 patient-years among those receiving intensive-dose therapy (mean [SD] 18.9 [5.2] cases per 1000 patient-years with high-dose statin treatment vs 16.9 [5.5] cases per 1000 patient-years with moderate-dose therapy), ...
Exercise Training Effects on Skeletal Muscle Performance in Long-Term Statin Users A moderate intensity endurance and resistance exercise training program improves muscle performance, capillarization, and mitochondrial content in both asymptomatic and symptomatic statin users and nonstatin using adults, ...
Signal-to-noise ratio (mean signal intensity/standard deviation of signal intensity) of the CTDE scan was estimated using a 10-mm2 region of interest in the left ventricle. MDCT Radiation Exposure Estimation Effective radiation dose exposure for each component of the MDCT comprehensive protocol (...
(4) Conclusions: In high-complex RA PCI, moderate/low-intensity statin therapy is not inferior to high-intensity statin therapy in Korea. Keywords: statin intensity; rotablation; percutaneous coronary intervention1. Introduction Coronary artery disease (CAD) is a substantial global health issue, and...
Objectives: This systematic review is conducted to evaluate the effect of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on body composition and cardiorespiratory fitness (CRF) in the young and middle-aged. Meth
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All least-square mean reductions in MSSBP and MSDBP (baseline to Week 3 and end of study) were significantly greater with triple therapy than with each dual therapy in the overall population and the severe systolic subgroup (baseline MSSBP a 180 mmHg; except vs. Aml 10 mg/Val 320 mg at...
LDL cholesterol levels of < 70 mg/dL at 1, 2, and 3 years were more frequently achieved in the ezetimibe combination group than in the high-intensity statin monotherapy group (all P < 0.001) in both sexes. There were no significant interactions between sex and treatment groups regarding the...